Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes
Autor: | Cherie T. Ng, Juan L. Mendoza, K. Christopher Garcia, Michael B. A. Oldstone |
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Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
Biochemistry Genetics and Molecular Biology(all) Interferon-alpha/beta receptor Alpha interferon Alpha (ethology) Bacterial Infections Receptor Interferon alpha-beta Biology General Biochemistry Genetics and Molecular Biology Article Pathogenesis 03 medical and health sciences 030104 developmental biology Interferon Virus Diseases Immunology Interferon Type I medicine Animals Humans Interleukin 29 Beta type Type 1 interferon medicine.drug |
Zdroj: | Cell. 164(3):349-352 |
ISSN: | 0092-8674 |
DOI: | 10.1016/j.cell.2015.12.027 |
Popis: | Type I interferon (IFN-I) elicits a complex cascade of events in response to microbial infection. Here, we review recent developments illuminating the large number of IFN-I species and describing their unique biologic functions. |
Databáze: | OpenAIRE |
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