T‐wave heterogeneity in standard resting 12‐lead ECGs is associated with 90‐day cardiac mortality in women following emergency department admission: A nested case–control study

Autor: Sofia A. Medeiros, Giovanna C. Pedreira, Felipe R. Monteiro, Edward Ullman, Fernanda Tessarolo Silva, Bruce D. Nearing, Ana B. Rabêlo Evangelista, Ernest V. Gervino, Richard L. Verrier
Rok vydání: 2021
Předmět:
Male
cardiac mortality
Acute coronary syndrome
medicine.medical_specialty
emergency department
T‐wave heterogeneity
Myocardial Infarction
electrocardiogram
030204 cardiovascular system & hematology
Risk Assessment
Electrocardiography
03 medical and health sciences
Sex Factors
0302 clinical medicine
Physiology (medical)
Internal medicine
T wave
medicine
Humans
Diseases of the circulatory (Cardiovascular) system
030212 general & internal medicine
Myocardial infarction
Acute Coronary Syndrome
Survival analysis
Aged
repolarization
business.industry
Hazard ratio
Original Articles
General Medicine
Odds ratio
Emergency department
medicine.disease
Case-Control Studies
RC666-701
Nested case-control study
Original Article
Female
Emergency Service
Hospital
Cardiology and Cardiovascular Medicine
business
Zdroj: Annals of Noninvasive Electrocardiology, Vol 26, Iss 3, Pp n/a-n/a (2021)
Annals of Noninvasive Electrocardiology
ISSN: 1542-474X
1082-720X
DOI: 10.1111/anec.12826
Popis: Background We investigated whether T‐wave heterogeneity (TWH) can identify patients who are at risk for near‐term cardiac mortality. Methods A nested case–control analysis was performed in the 888 patients admitted to the Emergency Department (ED) of our medical center in July through September 2018 who had ≥2 serial troponin measurement tests within 6 hr for acute coronary syndrome evaluation to rule‐in or rule‐out the presence of acute myocardial infarction. Patients who died from cardiac causes during 90 days after ED admission were considered cases (n = 20; 10 women) and were matched 1:4 on sex and age with patients who survived during this period (n = 80, 40 women). TWH, that is, interlead splay of T waves, was automatically assessed from precordial leads by second central moment analysis. Results TWHV4‐6 was significantly elevated at ED admission in 12‐lead resting ECGs of female patients who died of cardiac causes during the following 90 days compared to female survivors (100 ± 14.9 vs. 40 ± 3.6 µV, p
Databáze: OpenAIRE
Externí odkaz: