Association of Sex With Risk of 2-Year Revision Among Patients Undergoing Total Hip Arthroplasty
| Autor: | Xinyan Zheng, Danica Marinac-Dabic, Raquel Peat, Laura E. Gressler, Amanda Chen, Liz Paxton, Alexander Liebeskind, Art Sedrakyan, Terri Cornelison, Vincent J. Devlin, Jialin Mao |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Reoperation medicine.medical_specialty Arthroplasty Replacement Hip Population MEDLINE Risk Assessment Cohort Studies Postoperative Complications Sex Factors Risk Factors Internal medicine Cox proportional hazards regression medicine Humans Revision rate Sex Distribution education Aged Original Investigation education.field_of_study business.industry Research Hazard ratio General Medicine Middle Aged United States Prosthesis Failure Online Only Treatment Outcome Orthopedics Female Hip Prosthesis business Cohort study Total hip arthroplasty |
| Zdroj: | JAMA Network Open |
| ISSN: | 2574-3805 |
| Popis: | This cohort study evaluates the association between sex and 2-year revision after total hip arthroplasty as well as the association between sex and risk of revision. Key Points Question Is there an association between sex and the 2-year revision rate after total hip arthroplasty? Findings In this cohort study of 132 826 patients with osteoarthritis, no clinically meaningful difference was found in all-cause rates of revision between men and women. The absolute difference in overall revision risk among men and women was small at 1- and 2-year follow-up. Meaning The findings suggest that sex is not associated with the risk of 2-year revision after total hip arthroplasty. Importance The worldwide population is aging and includes more female individuals than male individuals, with higher rates of total hip arthroplasty (THA) among female individuals. Although research on this topic has been limited to date, several studies are currently under way. Objectives To evaluate the association between sex and 2-year revision after THA. Design, Setting, and Participants This cohort study used data from statewide databases in New York and California between October 1, 2015, and December 31, 2018. Patients 18 years or older with osteoarthritis who underwent THA and had sex recorded in the database were included in the analysis. Exposure Total hip arthroplasty. Main Outcomes and Measures The outcome of interest was the difference in early, all-cause revision surgery rates after primary THA between women and men. The association of sex with the revision rate was examined using Cox proportional hazards regression analysis. Results Of 132 826 patients included in the study, 74 002 (55.7%) were women; the mean (SD) age was 65.9 (11.0) years, and the median follow-up time was 1.3 years (range, 0.0-3.0 years). The 2-year revision rate was 2.5% (95% CI, 2.4%-2.6%) among women and 2.1% (95% CI, 2.0%-2.2%) among men. After adjusting for demographic characteristics, comorbidities, and facility volume, a minimal clinically meaningful difference was observed in revision rates despite women having a higher risk of all-cause revision compared with men (hazard ratio, 1.16; 95% CI, 1.07-1.26; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|