Long-Term Follow-Up in a Girl with Cystic Fibrosis and Diabetes Since the First Year of Life
| Autor: | Enza Mozzillo, Valeria Raia, A. Casale, Adriana Franzese, Valentina Fattorusso |
|---|---|
| Přispěvatelé: | Fattorusso, Valentina, Casale, Alida, Raia, Valeria, Mozzillo, Enza, Franzese, Adriana |
| Rok vydání: | 2017 |
| Předmět: |
Pediatrics
medicine.medical_specialty Cystic fibrosis-related diabete Endocrinology Diabetes and Metabolism medicine.medical_treatment media_common.quotation_subject Cystic fibrosis-related diabetes Case Report 030209 endocrinology & metabolism Cystic fibrosis Diabetes in infancy 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Diabetes mellitus Glucose metabolism derangements Internal Medicine medicine Glargine Girl media_common Glucose metabolism derangement Insulin glargine business.industry Insulin Infant medicine.disease Comorbidity Surgery Natural history Cystic fibrosi business medicine.drug |
| Zdroj: | Diabetes Therapy |
| ISSN: | 1869-6961 1869-6953 |
| Popis: | Diabetes mellitus is the most common comorbidity in cystic fibrosis (CF). Recently, more attention has been paid to early glucose metabolism derangements (GMDs). The subject of this report is a female patient, affected by CF since 3 months of age. She presented with intermittent diabetes during early childhood. At the age of 10 years, oral glucose tolerance test (OGTT) was performed and showed glucose intolerance (IGT) status; glargine insulin therapy was started. At the age of 13 years, CF-related diabetes with fasting hyperglycemia occurred, so rapid insulin at meals was added. During the following year, clinical and nutritional status improved. Stable clinical conditions were observed in the following 3 years. This is the first case of very long-term follow-up concerning a CF patient with GMDs. Our case confirms the importance of paying attention to early GMDs in very young CF patients and seems to suggest that earlier therapy could ameliorate CF natural history. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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