Pressure and flow properties of dual-lumen cannulae for extracorporeal membrane oxygenation
| Autor: | Martijn Gilbers, Roberto Lorusso, Jan Belohlavek, Lars Mikael Broman, Leen Vercaemst, Lisa Prahl Wittberg, Luisa Perry da Câmara, Maximilian V. Malfertheiner, Matteo Di Nardo, Fabio Silvio Taccone, Federico Pappalardo, C Jerker Westlund, Mirko Belliato, Justyna Swol, Nicholas A Barrett |
|---|---|
| Přispěvatelé: | RS: Carim - H08 Experimental atrial fibrillation, RS: Carim - V04 Surgical intervention, RS: Carim - B01 Blood proteins & engineering, MUMC+: MA Med Staf Artsass CTC (9), CTC, MUMC+: MA Med Staf Spec CTC (9) |
| Rok vydání: | 2020 |
| Předmět: |
cannula
BLOOD medicine.medical_treatment water Vascular access Lumen (anatomy) Extracorporeal AWAKE Pressure Extracorporeal membrane oxygenation medicine Humans Radiology Nuclear Medicine and imaging In patient pressure-flow Advanced and Specialized Nursing venous business.industry General Medicine extracorporeal membrane oxygenation PERFORMANCE Cannula NON-NEWTONIAN PROPERTIES RECIRCULATION THROMBOSIS Anesthesia dual lumen ECMO Cardiology and Cardiovascular Medicine Flow properties business Safety Research |
| Zdroj: | Perfusion, 35(8), 736-744. SAGE Publications Ltd |
| ISSN: | 1477-111X 0267-6591 |
| DOI: | 10.1177/0267659120926009 |
| Popis: | Introduction: In the last decade, dual-lumen cannulae have been increasingly applied in patients undergoing extracorporeal life support. Well-performing vascular access is crucial for efficient extracorporeal membrane oxygenation support; thus, guidance for proper cannulae size is required. Pressure–flow charts provided by manufacturers are often based on tests performed using water, rarely blood. However, blood is a shear-thinning and viscoelastic fluid characterized by different flow properties than water. Methods: We performed a study evaluating pressure–flow curves during standardized conditions using human whole blood in two commonly available dual-lumen cannulae used in neonates, pediatric, and adult patients. Results were merged and compared with the manufacturer’s corresponding curves obtained from the public domain. Results: The results showed that using blood as compared with water predominantly influenced drainage flow. A 10-80% higher pressure-drop was needed to obtain same drainage flow (hematocrit of 26%) compared with manufacturer’s water charts in 13-31 Fr bi-caval dual-lumen cannulae. The same net difference was found in cavo-atrial cannulae (16-32 Fr), where a lower drainage pressure was required (Hct of 26%) compared with the manufacturer’s test using blood with an Hct of 33%. Return pressure–flow data were similar, independent whether pumping blood or water, to the data reported by manufacturers. Conclusion: Non-standardized testing of pressure–flow properties of extracorporeal membrane oxygenation dual-lumen cannulae prevents an adequate prediction of pressure–flow results when these cannulae are used in patients. Properties of dual-lumen cannulae may vary between sizes within same cannula family, in particular concerning the drainage flow. |
| Databáze: | OpenAIRE |
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