FigureS2 from CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

Autor:	A. Keith Stewart, Esteban Braggio, Jonathan Ahmann, Robert A. Stewart, Moulun Luo, Patrick G. Votruba, Patrick Jedlowski, Laura A. Bruins, Yuan Xiao Zhu, K. Martin Kortüm, Chang-Xin Shi
Rok vydání:	2023
DOI:	10.1158/1535-7163.22509904
Popis:	A&B. Cloned KMS11 cells with deleted PSMC6 had no difference for response against dexamethasone and melphalan. C. The 26S proteasome has no significant change in MM cells without PSMC6. D&E. Deficiency of PSMC1 to 5 had similar influence on sensitivity of MM cells against BTZ treatment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fea55ddb848237f78029dbda338044c https://doi.org/10.1158/1535-7163.22509904 Zobrazit plný text záznamu