High prevalence of deep venous thrombosis in non-severe COVID-19 patients hospitalized for a neurovascular disease
| Autor: | Amadou Talibe Balde, Bernard Geny, Olivier Rouyer, Damaris Jupiter, Irène Nora Pierre-Paul, Valérie Wolff, Daniela Bindila |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
lcsh:Diseases of the circulatory (Cardiovascular) system
medicine.medical_specialty Coronavirus disease 2019 (COVID-19) deep vein venous thrombosis doppler ultrasound scanning Disease 030204 cardiovascular system & hematology Asymptomatic law.invention 03 medical and health sciences 0302 clinical medicine law medicine.artery Intensive care Internal medicine Occlusion medicine cardiovascular diseases stroke unit Original Paper High prevalence business.industry Neurovascular bundle medicine.disease Intensive care unit Pulmonary embolism neurovascular disease Venous thrombosis Neurology covid-19 lcsh:RC666-701 Ophthalmic artery Neurology (clinical) medicine.symptom Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery |
| Zdroj: | Cerebrovascular Diseases Extra, Vol 10, Iss 3, Pp 174-180 (2020) Cerebrovascular Diseases Extra |
| DOI: | 10.1101/2020.09.03.20187344 |
| Popis: | Introduction: Severe SARS-CoV-2 infection induces COVID-19 along with venous thromboembolic occurrences particularly in intensive care units. For non-severe COVID-19 patients affected by neurovascular diseases, the prevalence of deep venous thrombosis (DVT) is unknown. The aim of our study was to report data obtained after systematic Doppler ultrasound scanning (DUS) of lower limbs in such patients. Methods: Between March 20 and May 2, 2020, the deep venous system of 13 consecutive patients diagnosed with neurovascular diseases and non-severe COVID-19 was investigated with a systematic bedside DUS. Results: Thirteen patients were enrolled in the study including 9 acute ischaemic strokes, 1 occlusion of the ophthalmic artery, 1 transient ischaemic attack, 1 cerebral venous thrombosis and 1 haemorrhagic stroke. On admission, the median National Institute of Health Stroke Scale (NIHSS) score was of 6 (IQR, 0–20). During the first week after admission, and despite thromboprophylaxis, we found a prevalence of 38.5% of asymptomatic calves’ DVT (n = 5). One patient developed a symptomatic pulmonary embolism and 2 other patients died during hospitalization. The outcome was positive for the other patients with a discharge median NIHSS score of 1 (IQR, 0–11). Discussion/Conclusion: Despite thromboprophylaxis, systematic bedside DUS showed a high prevalence (38.5%) of asymptomatic DVT in non-severe COVID-19 patients suffering from a neurovascular disease. In the absence of a reliable marker of DVT, we suggest that this non-invasive investigation could be an interesting tool to monitor peripheral venous thrombotic complications in such patients. |
| Databáze: | OpenAIRE |
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