Association of E484K Spike Protein Mutation With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Vaccinated Persons: Maryland, January-May 2021

Autor:	Robert W. Myers, C. Paul Morris, Tim Blood, Katherine A. Feldman, Venkata R. Vepachedu, Jacques Ravel, Liore Klein, Eric N. Keller, Judie Hyun, Thelonious W. Williams, Monique Duwell, Curi Kim, David Blythe, Catherine Dominguez, Kenneth A. Feder, Ami Patel, Heba H. Mostafa
Rok vydání:	2021
Předmět:	Microbiology (medical) 2019-20 coronavirus outbreak COVID-19 Vaccines Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) R.1 B.1.351 B.1.526.1 variants of concern B.1.526 COVID-19 vaccine effectiveness Medicine Humans B.1.429 Maryland business.industry SARS-CoV-2 Brief Report E484K Spike Protein COVID-19 sequencing Virology Vaccination genomic surveillance L452R Infectious Diseases AcademicSubjects/MED00290 Mutation (genetic algorithm) Mutation Spike Glycoprotein Coronavirus B.1 business
Zdroj:	Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
ISSN:	1537-6591
Popis:	Among 9048 people infected with SARS-CoV-2 between January and May 2021 in Maryland, in regression-adjusted analysis, SARS-CoV-2 viruses carrying the spike protein mutation E484K were disproportionately prevalent among persons infected after full vaccination against COVID-19 compared with infected persons who were not fully vaccinated (aOR, 1.96; 95% CI: 1.36–2.83).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd91169ab5e59841ff9f1200bbb5f99 https://pubmed.ncbi.nlm.nih.gov/34473242 Zobrazit plný text záznamu