Outcomes of treatment of mammary analogue secretory carcinoma of the parotid gland
| Autor: | J.H. Kim, Dong-Suk Lee, Tae-Mi Yoon, Joon-Kyoo Lee, S.C. Lim |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Resection 03 medical and health sciences 0302 clinical medicine Mammaglobin stomatognathic system Biomarkers Tumor medicine Humans Parotid Gland 030223 otorhinolaryngology Retrospective Studies Salivary gland biology business.industry Mammary analogue secretory carcinoma Salivary Gland Neoplasms Aspiration cytology Parotid gland Radiation therapy Treatment Outcome medicine.anatomical_structure Otorhinolaryngology 030220 oncology & carcinogenesis biology.protein Immunohistochemistry Surgery Mammary Analogue Secretory Carcinoma Radiology Neoplasm Recurrence Local Oral Surgery business |
| Zdroj: | British Journal of Oral and Maxillofacial Surgery. 58:158-162 |
| ISSN: | 0266-4356 |
| Popis: | Mammary analogue secretory carcinoma (MASC) of the salivary gland is a newly-described, rare, malignant tumour. Few patients present with MASC of the parotid gland, so the exact characteristics, outcomes of treatment, and prognosis are unknown. The aim of this study was to analyse the clinical features and outcomes of treatment of MASC of the parotid gland in patients being treated at a single hospital. Five patients with histopathologically-confirmed MASC of the parotid gland between January 2015 and August 2018 were retrospectively enrolled. In all cases preoperative fine-needle aspiration cytology had failed to provide an accurate diagnosis. All patients underwent a macroscopically complete oncological resection. Two patients had postoperative radiotherapy (RT). On immunohistochemical examination all tumours stained for S-100 and mammaglobin but not for DOG1. There were no regional recurrences or distant metastases in any of the patients at their last follow-up. We obtained good results for patients with MASC of the parotid gland with surgical treatment and postoperative RT. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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