Oleic amide derivatives as small molecule stimulators of the human proteasome's core particle

Autor:	Saayak Halder, Nathaniel J. Macatangay, Breanna L. Zerfas, Andres F. Salazar-Chaparro, Darci J. Trader
Rok vydání:	2022
Předmět:	Pharmacology Organic Chemistry Drug Discovery Pharmaceutical Science Molecular Medicine Biochemistry
Zdroj:	RSC medicinal chemistry. 13(9)
ISSN:	2632-8682
Popis:	A series of oleic acid amide derivatives were generated as potential small molecule stimulators of the 20S core particle of the proteasome (20S CP), with the goal of increasing the protein degradation rate via the ubiquitin-independent pathway.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd83ac92c86d828dfdb5770c26b7d05 https://pubmed.ncbi.nlm.nih.gov/36324496 Zobrazit plný text záznamu