A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries
| Autor: | Kristin Hofsø, Anders Perner, Nicolai Haase, Salla Kattainen, Stepani Bendel, Eirik Alnes Buanes, Linda B. Kristinsdottir, Reidar Kvåle, Tero Varpula, Martin I. Sigurdsson, Michelle S Chew, Jon Henrik Laake, Hans Flaatten, Sten Walther, Matti Reinikainen, Johanna Hästbacka |
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| Přispěvatelé: | HUS Perioperative, Intensive Care and Pain Medicine, Clinicum |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Adult
medicine.medical_specialty SARS‐CoV2 Critical Care COVID19 medicine.medical_treatment Disease law.invention 03 medical and health sciences 0302 clinical medicine COVID‐19 law Pandemic medicine Humans 030212 general & internal medicine Renal replacement therapy Mortality Pandemics Research Articles Aged Mechanical ventilation Descriptive statistics SARS-CoV-2 business.industry COVID-19 030208 emergency & critical care medicine Hydroxychloroquine General Medicine medicine.disease Intensive care unit Comorbidity 3142 Public health care science environmental and occupational health 3. Good health Intensive Care Units Anesthesiology and Pain Medicine Nordic Emergency medicine SARS-COv2 business Research Article medicine.drug |
| Zdroj: | Acta Anaesthesiologica Scandinavica Chew, M S, Kattainen, S, Haase, N, Buanes, E A, Kristinsdottir, L B, Hofsø, K, Laake, J H, Kvåle, R, Hästbacka, J, Reinikainen, M, Bendel, S, Varpula, T, Walther, S, Perner, A, Flaatten, H K & Sigurdsson, M I 2022, ' A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries ', Acta Anaesthesiologica Scandinavica, vol. 66, no. 1, pp. 56-64 . https://doi.org/10.1111/aas.13983 |
| DOI: | 10.1111/aas.13983 |
| Popis: | Background We sought to provide a description of surge response strategies and characteristics, clinical management and outcomes of patients with severe COVID-19 in the intensive care unit (ICU) during the first wave of the pandemic in Denmark, Finland, Iceland, Norway and Sweden. Methods Representatives from the national ICU registries for each of the five countries provided clinical data and a description of the strategies to allocate ICU resources and increase the ICU capacity during the pandemic. All adult patients admitted to the ICU for COVID-19 disease during the first wave of COVID-19 were included. The clinical characteristics, ICU management and outcomes of individual countries were described with descriptive statistics. Results Most countries more than doubled their ICU capacity during the pandemic. For patients positive for SARS-CoV-2, the ratio of requiring ICU admission for COVID-19 varied substantially (1.6-6.7%). Apart from age (proportion of patients aged 65 years or over between 29-62%), baseline characteristics, chronic comorbidity burden and acute presentations of COVID-19 disease were similar among the five countries. While utilization of invasive mechanical ventilation was high (59-85%) in all countries, the proportion of patients receiving renal replacement therapy (7-26%) and various experimental therapies for COVID-19 disease varied substantially (e.g. use of hydroxychloroquine 0-85%). Crude ICU mortality ranged from 11% to 33%. Conclusion There was substantial variability in the critical care response in Nordic ICUs to the first wave of COVID-19 pandemic, including usage of experimental medications. While ICU mortality was low in all countries, the observed variability warrants further attention. |
| Databáze: | OpenAIRE |
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