Decline in syphilis seroprevalence among females of reproductive age in Northern Cape Province, South Africa, 2003–2012: utility of laboratory-based information
| Autor: | Alfred Musekiwa, Ngormbu Jusu Ballah, Simbarashe Takuva, Seymour Williams, Lazarus R. Kuonza, Gloria De Gita |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Adolescent Reproductive age Dermatology Article South Africa Young Adult 03 medical and health sciences 0302 clinical medicine Laboratory service Seroepidemiologic Studies Cape medicine Humans Seroprevalence Pharmacology (medical) Longitudinal Studies Syphilis 030212 general & internal medicine Young adult Child Disease burden 030219 obstetrics & reproductive medicine business.industry Public Health Environmental and Occupational Health Middle Aged medicine.disease Infectious Diseases Congenital syphilis Epidemiological Monitoring Female Laboratories business Demography |
| Zdroj: | International Journal of STD & AIDS. 28:564-572 |
| ISSN: | 1758-1052 0956-4624 |
| DOI: | 10.1177/0956462416636727 |
| Popis: | Strengthening current surveillance systems for syphilis is important to track and monitor disease burden. We used routinely collected laboratory information to generate surveillance estimates for syphilis trends among women of reproductive age (12–49 years) in the Northern Cape Province, a high syphilis burden region (2003 [8.6%] to 2011 [3.8%]) in South Africa. We extracted records meeting inclusion criteria from the National Health Laboratory Service electronic database for the period 2003–2012. A total of 286,024 women were included in the analysis. Syphilis seropositivity decreased between 2003 (5.7%) and 2012 (1.8%); p trend = 0.001, which was largely consistent with findings reported in the annual national syphilis and HIV survey from 2003 (8.6%) to 2011 (3.8%). Annually for the period from 2003 to 2012 there was an approximate 14% reduction in the prevalence ratio of syphilis seroprevalence (PR = 0.86, 95% CI = 0.85–0.87, p |
| Databáze: | OpenAIRE |
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