Generation of singlet molecular oxygen by lipid hydroperoxides and nitronium ion
| Autor: | Marisa Helena Gennari de Medeiros, Alexsandra Cristina Scalfo, Paolo Di Mascio, Sayuri Miyamoto, Fernanda Manso Prado |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
inorganic chemicals
Lipid Peroxides Nitrogen Dioxide Oxidative phosphorylation Photochemistry 01 natural sciences Biochemistry Ion 03 medical and health sciences chemistry.chemical_compound polycyclic compounds Nitronium ion Physical and Theoretical Chemistry Spectroscopy 030304 developmental biology Ions 0303 health sciences Spectroscopy Near-Infrared Singlet Oxygen 010405 organic chemistry Chemistry General Medicine Hydrogen Peroxide 0104 chemical sciences Membrane Excited state LIPÍDEOS Nucleic acid Solvents Azide |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| Popis: | Singlet molecular oxygen is a reactive species involved in biological oxidative processes. The major cellular targets of singlet molecular oxygen are unsaturated fatty acids in the membrane, as well as nucleic acids and proteins. The aim of this study was to investigate whether lipids and commercial hydroperoxides generate singlet molecular oxygen, in presence of nitronium and activated nitronium ion. For this purpose, monomol light emitted in the near-infrared region (λ = 1270 nm) was used to monitor singlet molecular oxygen decay in different solvents, with different hydroperoxides and in the presence of azide. Direct measurements of the singlet molecular oxygen spectrum at 1270 nm recorded during the reaction between lipids and commercial hydroperoxides and nitronium ions unequivocally demonstrated the formation of this excited species. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|