National Prevalence and Risk Factors for Food Allergy and Relationship to Asthma: Results from the National Health and Nutrition Examination Survey 2005-2006
| Autor: | Andrew H. Liu, Scott H. Sicherer, Richard D. Cohn, A. Wesley Burks, S. Allan Bock, Robert A. Wood, M. Massing, Darryl C. Zeldin, Renee Jaramillo |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male National Health and Nutrition Examination Survey Adolescent Immunology Population Prevalence Eczema Article Young Adult Food allergy Risk Factors Environmental health medicine Immunology and Allergy Humans Risk factor education Child Asthma education.field_of_study business.industry Infant Rhinitis Allergic Seasonal Odds ratio Allergens Immunoglobulin E Middle Aged medicine.disease Nutrition Surveys United States Food Child Preschool Hay fever Female business Food Hypersensitivity |
| ISSN: | 2005-2006 |
| Popis: | Background The national prevalence and patterns of food allergy (FA) in the United States are not well understood. Objective We developed nationally representative estimates of the prevalence of and demographic risk factors for FA and investigated associations of FA with asthma, hay fever, and eczema. Methods A total of 8203 participants in the National Health and Nutrition Examination Survey 2005-2006 had food-specific serum IgE measured to peanut, cow's milk, egg white, and shrimp. Food-specific IgE and age-based criteria were used to define likely FA (LFA), possible FA, and unlikely FA and to develop estimates of clinical FA. Self-reported data were used to evaluate demographic risk factors and associations with asthma and related conditions. Results In the United States, the estimated prevalence of clinical FA was 2.5% (peanut, 1.3%; milk, 0.4%; egg, 0.2%; shrimp, 1.0%; not mutually exclusive). Risk of possible FA/LFA was increased in non-Hispanic blacks (odds ratio, 3.06; 95% CI, 2.14-4.36), males (1.87; 1.32-2.66), and children (2.04; 1.42-2.93). Study participants with doctor-diagnosed asthma (vs no asthma) exhibited increased risk of all measures of food sensitization. Moreover, in those with LFA, the adjusted odds ratio for current asthma (3.8; 1.5-10.7) and an emergency department visit for asthma in the past year (6.9; 2.4-19.7) were both notably increased. Conclusion Population-based serologic data on 4 foods indicate an estimated 2.5% of the US population has FA, and increased risk was found for black subjects, male subjects, and children. In addition, FA could be an under-recognized risk factor for problematic asthma. |
| Databáze: | OpenAIRE |
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