Effects of hormone replacement therapy or raloxifene on ambulatory blood pressure and arterial stiffness in treated hypertensive postmenopausal women

Autor: Otavio C. E. Gebara, Giuseppe M.C. Rosano, José Mendes Aldrighi, Monica A. Oliveira, L.ílian Soares da Costa, Valéria Siqueira Martins Rubim, Mauricio Wajngarten, Cantidio Drumond Neto
Rok vydání: 2004
Předmět:
Zdroj: The American Journal of Cardiology. 94:1453-1456
ISSN: 0002-9149
DOI: 10.1016/j.amjcard.2004.07.153
Popis: The administration of oral raloxifene in 30 postmenopausal hypertensive women was evaluated to demonstrate its effect on arterial stiffness. Casual and ambulatory blood pressure (BP) and pulse-wave velocity (PWV) data were obtained before and after patients received raloxifene, estrogen-progestin replacement therapy, or placebo in a randomized crossover study. It was shown that the 2 therapies decreased BP and carotid-femoral PWV, and the effect of raloxifene on vascular compliance was independent of the effects on BP.
Databáze: OpenAIRE