Improving safety in paediatric thyroidectomy by PTH measurements
| Autor: | María Gabriela Ropelato, Ignacio Bergadá, Ana Chiesa, Eugenia Elias, María Eugenia Rodríguez, Patricia Papendieck, Ana Vieites, Analia Freire, María Gabriela Ballerini |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
endocrine system
medicine.medical_specialty Hypoparathyroidism Endocrinology Diabetes and Metabolism medicine.medical_treatment Gastroenterology Endocrinology Postoperative Complications Internal medicine Pediatric surgery medicine Humans Risk factor Child Hypocalcemia business.industry Incidence (epidemiology) Thyroid Thyroidectomy Neck dissection medicine.disease Confidence interval medicine.anatomical_structure Parathyroid Hormone Calcium business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Clinical endocrinologyREFERENCES. 95(5) |
| ISSN: | 1365-2265 |
| Popis: | OBJETIVE We followed our previously reported algorithm based on intra and postoperative parathyroid hormone (PTH) levels to predict postthyroidectomy hypoparathyroid hypocalcemia. The objective of the study was to assess if this strategy is useful and safe to reduce hypocalcemia, hospitalisation length and postsurgery calcium sampling. DESIGN, PATIENTS, MEASSUREMENTS We classified our series of 66 patients according to their risk of hypoparathyroidism based on PTH determinations. We treated high-risk patients with calcium and vitamin D1-25 supplementation and obtained routine daily calcium samples to control low-risk patients until 48 h postsurgery. We compared the outcomes and overall results of this new approach with those of a historical control group of patients with equivalent PTH measurements who were treated only if they presented hypocalcemia. RESULTS In the high-risk subgroup (n = 30), five patients had hypocalcemia within the first 24 h. Compared with the high-risk control subgroup, the incidence of hypocalcemia fell from 100% to 17% (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text