Prevalence of Trypanosoma cruzi infection among Bolivian immigrants in the city of São Paulo, Brazil

Autor: Maria Aparecida Shikanai-Yasuda, Ruth Moreira Leite, Rubens Antonio da Silva, Expedito Ja Luna, Cássio Silveira, Célia Regina Furucho, Fernando Mussa Abujamra Aith, Dalva Marli Valério Wanderley, Camila Gonçalves Sátolo, Lia Mb Silva, Noemia Barbosa Carvalho, Nivaldo Carneiro Jr.
Jazyk: angličtina
Předmět:
Zdroj: Memórias do Instituto Oswaldo Cruz., Iss 0
Memórias do Instituto Oswaldo Cruz, Volume: 112, Issue: 1, Pages: 70-74, Published: 16 NOV 2016
Memórias do Instituto Oswaldo Cruz
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
ISSN: 1678-8060
Popis: With the urbanisation of the population in developing countries and the process of globalisation, Chagas has become an emerging disease in the urban areas of endemic and non-endemic countries. In 2006, it was estimated that the prevalence of Chagas disease among the general Bolivian population was 6.8%. The aim of the present study was to determine the prevalence of Trypanosoma cruzi infection among Bolivian immigrants living in Sao Paulo, Brazil. This study had a sample of 633 volunteers who were randomly selected from the clientele of primary care units located in the central districts of Sao Paulo, Brazil. Infection was detected by two different ELISA assays with epimastigote antigens, followed by an immunoblot with trypomastigote antigens as a confirmatory test. The prevalence of the infection was 4.4%. Risk factors independently associated with the infection were: a history of rural jobs in Bolivia, knowledge of the vector involved in transmission, and having relatives with Chagas disease. Brazil has successfully eliminated household vector transmission of T. cruzi, as well as its transmission by blood transfusion. The arrival of infected immigrants represents an additional challenge to primary care clinics to manage chronic Chagas disease, its vertical transmission, and the blood derivatives and organ transplant programs.
Databáze: OpenAIRE