Nanomedicine-Based Strategies for Diabetes: Diagnostics, Monitoring, and Treatment

Autor: Luke R. Lemmerman, Daniel Gallego-Perez, Raghavendra G. Mirmira, Devleena Das, Natalia Higuita-Castro
Rok vydání: 2020
Předmět:
Zdroj: Trends Endocrinol Metab
ISSN: 1043-2760
DOI: 10.1016/j.tem.2020.02.001
Popis: Traditional methods for diabetes management require constant and tedious glucose monitoring and insulin injections, impacting quality of life. The global diabetic population is expected to increase to 439 million, with approximately USD 490 billion in healthcare expenditures by 2030, imposing a significant burden on healthcare systems worldwide. Recent advances in nanotechnology have emerged as promising alternative strategies for the management of diabetes. For example, implantable nano-sensors are being developed for continuous glucose monitoring, new nanoparticle-based imaging approaches that quantify subtle changes in β cell mass can facilitate early diagnosis, and nanotechnology-based insulin delivery methods are being explored as novel therapies. Here, we provide a holistic summary of this rapidly advancing field compiling all aspects pertaining to the management of diabetes.
Databáze: OpenAIRE