Exophytic sinonasal papillomas and nasal florid papillomatosis: A retrospective study
| Autor: | Romain Glâtre, L. Brugel, Virginie Prulière-Escabasse, André Coste, Heloïse De Kermadec, Anne Gauthier, Emilie Bequignon, Cécile Badoual, Claire Parra, Issam Abd Alsamad |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Nasal tumor Nose Neoplasms Papillomatosis Risk Assessment Cohort Studies Young Adult 03 medical and health sciences 0302 clinical medicine medicine Humans Human papillomavirus 030223 otorhinolaryngology Nasal Septum Retrospective Studies Papilloma Inverted business.industry virus diseases Endoscopy Retrospective cohort study Middle Aged Prognosis medicine.disease Dermatology Survival Rate body regions Treatment Outcome Otorhinolaryngology Dysplasia 030220 oncology & carcinogenesis Papilloma Female Neoplasm Recurrence Local medicine.symptom Tomography X-Ray Computed business Paranasal Sinus Neoplasms |
| Zdroj: | Head & Neck. 40:740-746 |
| ISSN: | 1043-3074 |
| DOI: | 10.1002/hed.25042 |
| Popis: | Background Sinonasal exophytic papillomas are rare. The multifocal form, florid papillomatosis, has not been yet described in literature. We report on the clinical features and the management of the different forms of exophytic papilloma. Methods A retrospective study was conducted that included all patients with exophytic papilloma treated in our center over the past 12 years. We recorded clinical presentation, treatments, recurrences, pathology (p16 expression and human papillomavirus [HPV] status). Results We included 13 patients with a mean follow-up of 5 years. The main location of exophytic papilloma was the anterior part of the septum. Lesions were multifocal in 3 patients corresponding to florid papillomatosis. The main treatment was surgery. Cases of HPV-11 or HPV-6 were present in all forms of exophytic papilloma (dysplasia in 4 cases). Late recurrences occurred in 3 patients (2 patients with florid papillomatosis) over a period of 3 years. Conclusion Exophytic papilloma has 2 clinical presentations: localized and diffuse. Patients with florid papillomatosis should be monitored closely as recurrence seems to be frequent. |
| Databáze: | OpenAIRE |
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