Wavelength optimization in femtosecond laser corneal surgery
| Autor: | Caroline Crotti, Jean-Marc Legeais, Fatima Alahyane, Laura Kowalczuk, Donald A. Peyrot, Florent Aptel, Karsten Plamann, Florent Deloison, Michèle Savoldelli |
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| Přispěvatelé: | Laboratoire d'optique appliquée (LOA), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-École Nationale Supérieure de Techniques Avancées (ENSTA Paris), Service d'Ophtalmologie [Grenoble], Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-Hôpital Michallon, Laboratoire Biotechnologie et Œil, Université Paris Descartes - Paris 5 (UPD5)-Hôpital Hôtel-Dieu [Paris], ANR, ANR-06-TECSAN-0025,GRECO,Greffes de cornée automatisées par laser femtoseconde optimisé et système de contrôle aberrométrique(2006), ANR-08-TECS-0012,NOUGAT,Nouvel OUtil pour la chirurgie du Glaucome Assistée par laser femtoseconde et Tomographie par cohérence optique(2008), Laboratoire d'optique appliquée ( LOA ), École Nationale Supérieure de Techniques Avancées ( Univ. Paris-Saclay, ENSTA ParisTech ) -École polytechnique ( X ) -Centre National de la Recherche Scientifique ( CNRS ), Université Joseph Fourier - Grenoble 1 ( UJF ) -CHU Grenoble-Hôpital Michallon, Université Paris Descartes - Paris 5 ( UPD5 ) -Hôpital Hôtel-Dieu [Paris], ANR-06-TECSAN-0025,GRECO,Greffes de cornée automatisées par laser femtoseconde optimisé et système de contrôle aberrométrique ( 2006 ), ANR-08-TECS-0012,NOUGAT,Nouvel OUtil pour la chirurgie du Glaucome Assistée par laser femtoseconde et Tomographie par cohérence optique ( 2008 ), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Hôpital Michallon-CHU Grenoble-Université Joseph Fourier - Grenoble 1 (UJF), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), ANR-06-TECS-0025,GRECO,Greffes de cornée automatisées par laser femtoseconde optimisé et système de contrôle aberrométrique(2006) |
| Rok vydání: | 2013 |
| Předmět: |
genetic structures
Corneal Surgery Laser [SDV]Life Sciences [q-bio] Visual Acuity 01 natural sciences law.invention MESH: cornea keratoplasty transparency laser surgery surgery 0302 clinical medicine law Microscopy Penetration depth Ultrashort pulse laser transparency [PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics] [ PHYS.PHYS.PHYS-OPTICS ] Physics [physics]/Physics [physics]/Optics [physics.optics] Tissue Donors Wavelength Femtosecond MESH : cornea keratoplasty transparency laser surgery Lasers Excimer Laser beam quality medicine.medical_specialty Materials science [PHYS.PHYS.PHYS-BIO-PH]Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph] Corneal Stroma keratoplasty 010309 optics 03 medical and health sciences Optics Microscopy Electron Transmission [ PHYS.PHYS.PHYS-BIO-PH ] Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph] [ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathology cornea 0103 physical sciences medicine Humans [ SDV ] Life Sciences [q-bio] business.industry Corneal Topography Laser Surgery laser 030221 ophthalmology & optometry Microscopy Electron Scanning sense organs business Ultrashort pulse [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology Keratoplasty Penetrating |
| Zdroj: | Investigative Ophthalmology & Visual Science Investigative Ophthalmology & Visual Science, Association for Research in Vision and Ophthalmology, 2013, 2013 (54), pp.3340-3349. ⟨10.1167/ iovs.12-10694⟩ iovs.arvojournals.org/ Investigative Ophthalmology & Visual Science, Association for Research in Vision and Ophthalmology, 2013, 2013 (54), pp.3340-3349. 〈iovs.arvojournals.org/〉. 〈10.1167/ iovs.12-10694〉 Investigative Ophthalmology & Visual Science, Association for Research in Vision and Ophthalmology, 2013, 2013 (54), pp.3340-3349. ⟨10.1167/iovs.12-10694⟩ |
| ISSN: | 1552-5783 0146-0404 |
| Popis: | PURPOSE. To evaluate the influence of wavelength on penetration depth and quality of femtosecond laser corneal incisions in view of optimizing procedures in corneal surgery assisted by ultrashort pulse lasers. METHODS. We performed penetrating and lamellar incisions on eye bank corneas using several ultrashort pulse laser sources. Several wavelengths within the near-infrared and shortwaveinfrared wavelength range were used and the pulse energy was varied. The corneas were subsequently analyzed using light microscopy as well as transmission and scanning electron microscopy. RESULTS. We found higher penetration depths and improved incision quality when using wavelengths close to k ¼ 1650 nm rather than the wavelength of k ¼ 1030 nm typical in current clinical systems. Optical micrographs show an improvement of the penetration depth by a factor of 2 to 3 while maintaining a good incision quality when using the longer wavelength. These results were confirmed with micrographs obtained with transmission and scanning electron microscopy. CONCLUSIONS. A wavelength change from the standard 1030 nm to 1650 nm in corneal surgery assisted by ultrashort pulse laser considerably reduces light scattering within the tissue. This results in a better preservation of the laser beam quality in the volume of the tissue, particularly when working at depths required for deep lamellar or penetrating keratoplasty. Using this wavelength yields improved penetration depths into the tissue; it permits use of lower energies for any given depth and thus reduces unwanted side effects as thermal effects. |
| Databáze: | OpenAIRE |
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