Non-invasive measurement of total respiratory compliance and resistance in cats
| Autor: | Ephraim Bar-Yishay, Alex Putilov, Hylton Bark, Ana Epstein, Simon Godfrey |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Physiology Pulmonary compliance Statistics Nonparametric Pulmonary function testing Internal medicine Occlusion medicine Tidal Volume Animals Lung volumes Expiration Respiratory system Lung Compliance Monitoring Physiologic Analysis of Variance Lung business.industry General Neuroscience Airway Resistance Forced Expiratory Flow Rates respiratory system Reference Standards Surgery Respiratory Function Tests medicine.anatomical_structure Cardiology Cats Respiratory Mechanics Airway business Pulmonary Ventilation |
| Zdroj: | Respiratory physiologyneurobiology. 156(2) |
| ISSN: | 1569-9048 |
| Popis: | We adapted non-invasive techniques developed for human infants to measure total respiratory system compliance (Crs) and resistance (Rrs) in 21 healthy cats. The animals breathed through a face mask attached to a respiratory circuit and measurements were taken of changes in lung volume and airway pressure during brief occlusions of the airway at different lung volumes. The slope of the plot of change in volume against airway pressure yielded the multiple occlusion Crs with a mean (±95%CI) value of 6.8 (6.3–7.3) ml/cm H2O. In 12 animals measurements were made by the single breath technique in which occlusion was made early in expiration and on release, a plot of the subsequent relaxed expiratory flow and volume yielded the time constant (τrs), Crs and Rrs with mean (±95%CI) values of 0.27 (0.22–0.31) s, 7.0 (6.1–7.8) ml/cm H2O, and 38.7 (33.7–43.6) cm H2O/l/s, respectively. Rrs was significantly correlated inversely with forced expiratory flow at resting lung volume (V’maxFRC). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect