Effect of Oocyte Retrieval from a Small Leading Follicle in Fixed-Schedulein vitroFertilization Program

Autor: Seiichiro Nagai, Shuji Hirata, Kaoruko Mizuno, Junzo Kato, Tsuyoshi Kasai, Takehiko Yasumizu
Rok vydání: 1997
Předmět:
Zdroj: Journal of Obstetrics and Gynaecology Research. 23:165-169
ISSN: 1341-8076
DOI: 10.1111/j.1447-0756.1997.tb00826.x
Popis: Objective: To evaluate the propriety of oocyte retrieval (OR) from a small leading follicle during a fixed-schedule in vitro fertilization (IVF) program. Methods: OR was fixed only to take place on Wednesdays. Gonadotropin-releasing hormone agonist treatment was initiated on the first day of the cycle, human menopausal gonadotrophin was given for 7 days starting on the next Monday, and human chorionic gonadotrophin (hCG) was given on the Tuesday before the OR. Patients were divided into 2 groups according to the follicular size observed before the day of hCG administration: Group 1 (141 cycles), with follicles > 16 mm in mean diameter; and Group 2 (38 cycles) with follicles of 10 to 16 mm in mean diameter. Results: Fertilization rates and the incidence of mature oocytes were higher in Group 1 than in Group 2. However, the mean number of oocytes recovered and pregnancy rates were similar in the 2 groups. Conclusion: It is worthwhile to retrieve the oocyte from a small leading follicle in a fixed-schedule IVF program.
Databáze: OpenAIRE