Accuracy of hysteroscopic diagnosis of endometrial hyperplasia: a retrospective study of 323 patients
| Autor: | Delia Garzia, Giancarlo Garuti, Massimo Luerti, Monica Colonnelli, Fulvia Cellani |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
medicine.medical_specialty Urology Hysteroscopy Endometrium Sensitivity and Specificity Atypical hyperplasia Predictive Value of Tests Medicine Humans Retrospective Studies Gynecology medicine.diagnostic_test business.industry Obstetrics and Gynecology Retrospective cohort study Hyperplasia medicine.disease Endometrial hyperplasia medicine.anatomical_structure Predictive value of tests Endometrial Hyperplasia Histopathology Female business |
| Zdroj: | Journal of minimally invasive gynecology. 12(3) |
| ISSN: | 1553-4650 |
| Popis: | STUDY OBJECTIVE: To evaluate the diagnostic accuracy of hysteroscopic view in endometrial hyperplasia. DESIGN: Retrospective study (Canadian Task Force classification II-2). SETTING: Public hospital in northern Italy. PATIENTS: Three hundred twenty-three patients suffering from endometrial hyperplasia out of 2251 women (1119 premenopausal and 1132 postmenopausal) who underwent office-based hysteroscopy from January 1996 through May 2004. INTERVENTION: Review of 2251 outpatient hysteroscopies carried out with 5- to 6-mm sheathed hysteroscopes and accomplished with blind or hysteroscopically targeted endometrial biopsies. MEASUREMENTS AND MAIN RESULTS: The pathologic report was considered the reference test. Hysteroscopic detection of focal or extensive endometrial thickening, irregular vascular network, architectural distortion and crowding of gland openings, and gland cyst formation were considered endoscopic features consistent with hyperplasia. Overall sensitivity, specificity, negative predictive values (NPV), and positive predictive values (PPV) of hysteroscopy in order to foresee a diagnosis of hyperplasia were calculated. These figures were calculated both in premenopausal and postmenopausal patients. Histopathology yielded a diagnosis of simple, complex, and atypical hyperplasia in 247, 51, and 25 patients, respectively. Hysteroscopy foresaw hyperplasia in 38.4% of patients with simple hyperplasia and in 58.9% of patients with complex or atypical hyperplasia. Normal hysteroscopic findings underestimated simple hyperplasia in 34 patients (13.7%) and complex or atypical hyperplasias in 1 patient (1.3%) (p |
| Databáze: | OpenAIRE |
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