Pneumocystis exhalation by infants developing Pneumocystis primary infection: putative infectious sources in hospitals and the community
| Autor: | F. Le Ny, C.V. Hoffmann, G. Nevez, Richard Pougnet, M. Artus, Pierrick Cros, L. Gaitan, Laurence Pougnet, S. Le Gal |
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| Přispěvatelé: | Groupe d'Étude des Interactions Hôte-Pathogène (GEIHP), Université d'Angers (UA), SFR UA 4208 Interactions Cellulaires et Applications Thérapeutiques (ICAT), Laboratoire de Parasitologie et Mycologiede [CHRU Brest], Centre Hospitalier Régional Universitaire de Brest (CHRU Brest) |
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
[SDV]Life Sciences [q-bio] 030231 tropical medicine Pneumocystis carinii Airborne transmission law.invention 03 medical and health sciences 0302 clinical medicine law parasitic diseases Pneumocystis jirovecii DNA Genotype Humans Medicine Pneumocystis jirovecii ComputingMilieux_MISCELLANEOUS Polymerase chain reaction 0303 health sciences biology Pneumocystis 030306 microbiology business.industry Pneumonia Pneumocystis Infant Exhalation General Medicine biology.organism_classification Virology Hospitals 3. Good health Infectious Diseases business |
| Zdroj: | Journal of Hospital Infection Journal of Hospital Infection, WB Saunders, 2021, ⟨10.1016/j.jhin.2021.04.015⟩ |
| ISSN: | 0195-6701 |
| DOI: | 10.1016/j.jhin.2021.04.015 |
| Popis: | Summary Pneumocystis jirovecii DNA was detected using a polymerase chain reaction assay in air samples collected using an air–liquid impaction device at 1 m distance from three out of 14 infants who had developed Pneumocystis primary infection. P. jirovecii genotype identification was successful in one out of three pairs of air samples. Matching of P. jirovecii genotypes between the nasopharyngeal and air samples suggested that P. jirovecii was effectively exhaled by the infected infant. These original results represent a proof of concept of the role of infants with primary pneumocystis infection as infectious sources of P. jirovecii in hospitals and in the community. |
| Databáze: | OpenAIRE |
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