Identification of benzothiazole-rhodanine derivatives as α-amylase and α-glucosidase inhibitors: Design, synthesis, in silico, and in vitro analysis

Autor:	Mahendra Gowdru Srinivasa, Natasha Naval Aggarwal, Banylla Felicity Dkhar Gatpoh, Madan Kumar Shankar, Kannika Byadarahalli Ravindranath, Pujar Gurubasavaraj Veeranna, Sheshagiri Dixit, Subhankar P. Mandal, Prashantha Kumar Bommenahally Ravanappa, Pukar Khanal, Revanasiddappa Bistuvalli Chandrashekarappa
Rok vydání:	2022
Předmět:	Molecular Docking Simulation Structure-Activity Relationship Rhodanine Structural Biology Hypoglycemic Agents Glycoside Hydrolase Inhibitors alpha-Glucosidases Benzothiazoles alpha-Amylases Molecular Biology
Zdroj:	Journal of molecular recognition : JMRREFERENCES. 35(8)
ISSN:	1099-1352
Popis:	A novel series of benzothiazole-rhodanine derivatives (A1-A10) were designed and synthesized, with the aim of developing possible antidiabetic agents and the spectral characterization of these compounds was done using infrared spectroscopy (IR), proton-nuclear magnetic resonance (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f82b26629568a26dd94259b7a37978f https://pubmed.ncbi.nlm.nih.gov/35349195 Zobrazit plný text záznamu Plný text