Aquaporin 9 regulates Leydig cell steroidogenesis in diabetes

Autor: Arun Kannan, Lezy Flora Mariajoseph-Antony, Antojenifer Panneerselvam, Chithra Loganathan, Diwakar Kiduva Jothiraman, Kumarasamy Anbarasu, Chidambaram Prahalathan
Rok vydání: 2022
Předmět:
Zdroj: Systems biology in reproductive medicine. 68(3)
ISSN: 1939-6376
Popis: Diabetes mellitus induced hyperglycemia increases oxidative stress, which contributes to impairment of male reproductive function. Aquaporins (AQPs) belong to a transmembrane protein superfamily containing 13 isoforms (AQP0-12), differentially expressed in various organs, and play a pivotal role in male reproductive function. In the current study, we investigated the relationship between AQPs and testicular steroidogenesis under hyperglycemia
Databáze: OpenAIRE
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