Selected Cardiovascular Risk Markers in Vegetarians and Subjects of General Population
| Autor: | Vladimír Urbánek, Martina Valachovicova, Jana Pribojova, Lucia Birošová |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Blood Glucose Male medicine.medical_treatment Population Physiology Reference range 03 medical and health sciences chemistry.chemical_compound Young Adult Insulin resistance High-density lipoprotein Risk Factors medicine Humans Insulin education Aged education.field_of_study 030109 nutrition & dietetics Cholesterol business.industry Public Health Environmental and Occupational Health Age Factors General Medicine Vegetarian nutrition Middle Aged medicine.disease Lipids chemistry Cardiovascular Diseases lipids (amino acids peptides and proteins) Female Risk assessment business Biomarkers Vegetarians |
| Zdroj: | Central European journal of public health. 25(4) |
| ISSN: | 1210-7778 |
| Popis: | Objective: Besides genetic factors there are environmental effects including nutritional habits which can influence the risk of age-related diseases. The aim of the study was to assess the age dependence of selected cardiovascular risk markers in two groups of subjects with different nutritional pattern. Methods: In 470 long-term vegetarians and 478 subjects of general population the following indicators were measured: total cholesterol, HDL-cholesterol, triacylglycerol, glucose, insulin concentrations, LDL-cholesterol, atherogenic index and insulin resistance IR(HOMA) were also calculated in studied subjects. Obtained data were evaluated according to age decades. Results: Vegetarian vs. non-vegetarian concentrations of total cholesterol, LDL-cholesterol, insulin, and values of atherogenic index and IR(HOMA) were significantly reduced in all age decades. Vegetarian vs. non-vegetarian triacalglycerol concentrations were significantly reduced from 4th-7th decade. Vegetarian average decade values of all lipid parameters were in reference range. In non-vegetarian group, the risk average values of total cholesterol (> 5.2 mmol/l) were found from 5th-7th decade, LDL-cholesterol (> 3.3 mmol/l) in 7th decade and atherogenic index (> 4) in 6th-7th decade. In vegetarians vs. non-vegetarians were noted the average decade values for total cholesterol ranging from 4.01-4.59 vs. 4.48-5.67 mmol/l, for triacylglycerols 1.00-1.33 vs. 1.13-1.74 mmol/l, for LDL-cholesterol 2.03-2.58 vs. 2.43-3.49 mmol/l, for atherogenic index 2.72-3.31 vs. 3.05-4.21 and for IR(HOMA) 0.99-1.15 vs. 1.15-1.84. Conclusion: Our data show significantly reduced mean age decade values of lipid and non-lipid cardiovascular risk markers in all adult vegetarians. Smaller changes of markers between decades compared to non-vegetarians document a protective effect of vegetarian nutrition in prevention of cardiovascular disease. |
| Databáze: | OpenAIRE |
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