| Autor: |
Diz-Muñoz, Alba, Romanczuk, Pawel, Weimiao Yu, Bergert, Martin, Ivanovitch, Kenzo, Salbreux, Guillaume, Carl-Philipp Heisenberg, Paluch, Ewa |
| Rok vydání: |
2016 |
| DOI: |
10.6084/m9.figshare.c.3632834_d2.v1 |
| Popis: |
Comparison of experimental and simulated cell trajectories (A). Examples of cell trajectories from wild-type cells in an MZoep host from low-magnification experiments (top) and from model simulations with the fitted parameters (bottom). All experimental (three-dimensional) trajectories were projected to the primary two-dimensional plane of their motion and rotated so that their average direction of migration aligns with the y-axis as in the simulations. Frames were captured at 90 s intervals for 3 h (~5.5–8.5 hpf). The red symbols indicate the points along the trajectory identified as tumbling events using the algorithm introduced in Sec. I C. Simulated cell trajectories corresponding to different experimental conditions (B). Examples of simulated cell trajectories for different values of model parameter τr with other parameters as fitted for wt cells in an MZoep embryo. (left) τr as fitted to the wt cells (τr = 8 min). (center) For long runs (τr = 25 min), which yield T r = T t - values consistent with results obtained from CAEzrin cells, and (right) short runs (τr = 4 min), which yield T r = T t , values consistent with the ones measured for ezrin-MO cells. (PDF 1651 kb) |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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