Acidosis láctica asociada a metformina. Caso clínico
| Autor: | Jorge Dreyse, Rodrigo Orozco, María José Pezzani, Felipe Quintana, Leonardo Soto, Tomás Regueira |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Metabolic acidosis General Medicine medicine.disease Gastroenterology Metformin Continuous hemofiltration Diarrhea Internal medicine Lactic acidosis Hemofiltration medicine Effective treatment Acidosis Lactic Renal Insufficiency medicine.symptom Adverse effect business Intensive care medicine medicine.drug |
| Zdroj: | Revista médica de Chile v.145 n.8 2017 SciELO Chile CONICYT Chile instacron:CONICYT |
| ISSN: | 0034-9887 |
| Popis: | Metformin-associated lactic acidosis is a severe and infrequent adverse event. Early diagnosis is essential to start an early treatment, which often has favorable results. We report a 56 years old non-insulin-requiring type 2 diabetic female who developed a severe metabolic acidosis associated with metformin in relation to an acute renal failure secondary to infectious diarrhea. Early treatment with bicarbonate and continuous hemofiltration allowed a quick improvement of the patient. Metformin-associated lactic acidosis has an elevated mortality (50-80%) and has a specific and effective treatment. Therefore, the condition must be born in mind. |
| Databáze: | OpenAIRE |
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