Bilateral orbital myeloid sarcoma as initial manifestation of acute myeloid leukemia
| Autor: | Salah Jenzeri, Riadh Messaoud, K. Hmidi, Adnene Laatiri, Moncef Khairallah, Sonia Zaouali, Wafa Ammari, Bahri Mahjoub, Leila Bacha |
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| Rok vydání: | 2006 |
| Předmět: |
Pathology
medicine.medical_specialty Myeloid Acute myeloblastic leukemia medicine.medical_treatment Antineoplastic Combined Chemotherapy Protocols medicine Myeloid sarcoma Exophthalmos Humans Sarcoma Myeloid Child Glucocorticoids Acute leukemia Chemotherapy business.industry Myeloid leukemia medicine.disease Ophthalmology Leukemia Leukemia Myeloid Acute medicine.anatomical_structure Orbital Neoplasms Drug Therapy Combination Female Sarcoma business Tomography X-Ray Computed |
| Zdroj: | International ophthalmology. 27(6) |
| ISSN: | 0165-5701 |
| Popis: | Granulocytic sarcoma is a rare orbital complication of acute leukemia. It concerns primarily children under 10 years of age suffering from primitive acute myeloid leukemia. The diagnosis is made by clinical examination, computed tomography and confirmed by haematological investigations. The treatment approach is based on chemotherapy associated with intravenous steroid therapy. We report the case of a 6-year-old girl who presented with bilateral proptosis revealing acute myeloid leukemia. The patient was treated by a combination of chemotherapeutic drugs in two phases, associated with intravenous steroids. After a follow-up period of 24 months, the patient was in complete remission. The diagnosis of granulocytic sarcoma should be considered in any orbital mass of uncertain origin, particularly if it is bilateral. Special stains and immunohistochemistry play an important role in the diagnosis. |
| Databáze: | OpenAIRE |
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