Cost-Effectiveness of Fecal Microbiota Transplantation in the Treatment of Recurrent Clostridium Difficile Infection: A Literature Review
| Autor: | Edmund Hsu, Keegan McNally, Leor T Arbel |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
genetic structures Cost effectiveness medicine.drug_class Antibiotics diarrhea Disease antibiotics Microbiology 03 medical and health sciences 0302 clinical medicine Medicine Routine clinical practice 030212 general & internal medicine Intensive care medicine cost effectiveness business.industry General Engineering Gastroenterology fecal microbiota transplantation Fecal bacteriotherapy Clostridium difficile c. difficle Quality Improvement Diarrhea Cost Effective Analyses 030211 gastroenterology & hepatology Preventive Medicine medicine.symptom business |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Clostridium difficile (C. difficile) is a common cause of antibiotic--associated diarrhea (AAD), being responsible for 15--25% of all AAD cases. The purpose of this literature review is to determine the cost-effectiveness of fecal microbiota transplantation (FMT) and how it compares in this regard to the standard treatments of choice for recurrent C. difficile infection (CDI). The review of the literature along with the evaluation of three comparative cost effective analyses yielded findings consistent with the view that FMT is the most cost-effective option in treating recurrent CDI. There are some (but considerably less) data indicating that FMT may be a cost effective strategy in treating initial CDI, as well. The superior cost-effectiveness of FMT as compared to the preferred standards of treatment for recurrent CDI suggest FMT use should become more integrated in routine clinical practice. Increased utilization of FMTs would allow for better control of this increasingly problematic disease as well as lower costs associated with its management. |
| Databáze: | OpenAIRE |
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