Are cord blood visfatin concentrations different depending on birth weight category?
| Autor: | Leonardo Mancillas-Adame, Cynthia M. Estrada-Zúñiga, Fernando J. Lavalle-González, Consuelo Treviño-Garza, Jesús Zacarías Villarreal-Pérez, Ana Lucía Lavalle-Cantú, Manuel Enrique de la O-Cavazos |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism Birth weight Gestational Age Umbilical cord Endocrinology Internal medicine medicine Birth Weight Humans Nicotinamide Phosphoribosyltransferase Nutrition and Dietetics business.industry Infant Newborn Gestational age Fetal Blood medicine.disease Cross-Sectional Studies medicine.anatomical_structure Cord blood Population study Gestation Small for gestational age Female medicine.symptom business Weight gain |
| Zdroj: | Endocrinología, Diabetes y Nutrición. 66:35-40 |
| ISSN: | 2530-0164 |
| Popis: | Background and objective Increased visceral adipose tissue mass is strongly associated to metabolic disorders. Visfatin is a visceral fat adipocytokine. There is epidemiological evidence of a link between a suboptimal gestational environment and a greater propensity to develop metabolic disease in adult life. The objective of this study was to establish whether visfatin concentrations in umbilical cord blood are different in newborns small for gestational age (SGA), appropriate for gestational age (AGA), and large for gestational age (LGA). Subjects and methods Term newborns from an university medical center were included in the study. A blood sample was taken from the umbilical cord vein of each baby immediately after birth. Visfatin was measured using an enzyme immunoassay in the study population, consisting of 35 subjects in the SGA group, 58 in the AGA group, and 35 in the LGA group. Results Cord blood visfatin concentrations were not different in the three groups, with respective values of 2.78 (1.86–4.49) ng/mL, 3.28 (1.98–4.97) ng/mL, and 3.46 (2.48–5.38) ng/mL in the SGA, AGA and LGA groups (p = 0.141). Gestational weight gain (GWG) (14.09 ± 6.37 kg) was negatively associated to visfatin levels (r = −0.218, p = 0.036). GWG is an independent predictor of visfatin concentrations (r2 = −0.067, p = 0.027). Conclusions There were no differences in cord blood visfatin concentrations depending on birth weight. GWG is an independent predictor of visfatin levels in the cord blood of term newborns. |
| Databáze: | OpenAIRE |
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