Effect of cryoballoon and radiofrequency ablation for pulmonary vein isolation on left atrial function in patients with nonvalvular paroxysmal atrial fibrillation: A prospective randomized study (Cryo‐LAEF study)
| Autor: | Spyridon Deftereos, Dimitrios A. Vrachatis, Constadina Aggeli, Dimosthenis Katritsis, Georgios Tsitsinakis, Georgios Giannopoulos, Dimitrios Tsiachris, Styliani Tsoukala, Michalis Efremidis, Konstantinos P. Letsas, Charalampos Kossyvakis |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Radiofrequency ablation medicine.medical_treatment Echocardiography Three-Dimensional Action Potentials 030204 cardiovascular system & hematology Cryosurgery Pulmonary vein law.invention 03 medical and health sciences 0302 clinical medicine Heart Rate Recurrence law Physiology (medical) Internal medicine Atrial Fibrillation medicine Humans Sinus rhythm Prospective Studies 030212 general & internal medicine Aged Ejection fraction Greece business.industry Atrial fibrillation Cryoablation Recovery of Function Middle Aged medicine.disease Ablation Confidence interval Treatment Outcome Pulmonary Veins Catheter Ablation Cardiology Atrial Function Left Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Cardiovascular Electrophysiology. |
| ISSN: | 1540-8167 1045-3873 |
| Popis: | BACKGROUND Isolation of the pulmonary veins (PVI) has become a mainstay in atrial fibrillation (AFib) therapy. Lesions in left atrial tissue lead to scar formation and this may affect left atrial function. METHODS Patients with paroxysmal AFib were randomly assigned in a 1:2 allocation scheme to radiofrequency (RF) ablation or cryoballoon. Real-time three-dimensional echocardiography was performed (under sinus rhythm in all cases) before ablation and at 1 and 3 months to evaluate the left atrial functional indices. The primary outcome measure was change in left atrial ejection fraction (LAEF) at 1 month. RESULTS 120 patients were randomized (80 to cryoballoon, 40 to RF). The absolute change in LAEF at 1 month was 4.0 (Q1-Q3, -0.1to 7.6)% in the cryoballoon group and -0.8 (Q1-Q3, -1.9 to 0.9)% in the RF group (P |
| Databáze: | OpenAIRE |
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