Temporally Irregular Mnemonic Persistent Activity in Prefrontal Neurons of Monkeys During a Delayed Response Task
| Autor: | Sridhar Raghavachari, Christos Constantinidis, Xiao Jing Wang, Jesper Tegnér, Matthew V. Chafee, Patricia S. Goldman-Rakic, Albert Compte |
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| Rok vydání: | 2003 |
| Předmět: |
Male
Neurons Delayed response Time Factors Physiology General Neuroscience Information processing Action Potentials Prefrontal Cortex Mnemonic Macaca mulatta Task (project management) medicine.anatomical_structure Memory Cortex (anatomy) Reaction Time medicine Animals Psychology Neuroscience Psychomotor Performance |
| Zdroj: | Journal of Neurophysiology. 90:3441-3454 |
| ISSN: | 1522-1598 0022-3077 |
| DOI: | 10.1152/jn.00949.2002 |
| Popis: | An important question in neuroscience is whether and how temporal patterns and fluctuations in neuronal spike trains contribute to information processing in the cortex. We have addressed this issue in the memory-related circuits of the prefrontal cortex by analyzing spike trains from a database of 229 neurons recorded in the dorsolateral prefrontal cortex of 4 macaque monkeys during the performance of an oculomotor delayed-response task. For each task epoch, we have estimated their power spectrum together with interspike interval histograms and autocorrelograms. We find that 1) the properties of most (about 60%) neurons approximated the characteristics of a Poisson process. For about 25% of cells, with characteristics typical of interneurons, the power spectrum showed a trough at low frequencies ( |
| Databáze: | OpenAIRE |
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