The P200 protein of Mycoplasma pneumoniae shows common features with the cytadherence-associated proteins HMW1 and HMW3
| Autor: | Helmut Hilbert, Helga Plagens, Thomas Proft, Richard Herrmann |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Mycoplasma pneumoniae
Proline Molecular Sequence Data Glutamic Acid Peptide medicine.disease_cause Bacterial Adhesion Microbiology Prokaryotic cytoskeleton Open Reading Frames Bacterial Proteins Genetics medicine Amino Acid Sequence Isoelectric Point Cloning Molecular Gene chemistry.chemical_classification biology Membrane Proteins General Medicine biology.organism_classification P200 Molecular Weight chemistry Biochemistry Genes Bacterial Cell Adhesion Molecules Bacteria |
| Zdroj: | Gene. 171(1) |
| ISSN: | 0378-1119 |
| Popis: | The gene coding for the P200 protein of the bacterium, Mycoplasma pneumoniae (Mp), was cloned and sequenced. The sequence-derived data and biochemical data indicated that P200 has several features in common with the well characterized cytadherence-associated proteins, HMW1 and HMW3. These features consist of abnormal migration in SDS-PAGE, a central acidic domain with a high Pro content, repeated peptide blocks within the Pro-rich domain and P200 partitioning similar to HMW1 and HMW3 in the insoluble fraction after extraction of Mp with the detergent Triton X-100. |
| Databáze: | OpenAIRE |
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