Ocular Adnexal Lymphoma: no evidence for bacterial DNA associated with lymphoma pathogenesis
| Autor: | Lilliana I. Moreno, John Matthews, Jeremy A. Dennis, Izidore S. Lossos, Gerald E. Byrne, Phillip Ruiz, Sander R. Dubovy |
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| Rok vydání: | 2008 |
| Předmět: |
DNA
Bacterial Polymerase Chain Reaction law.invention Pathogenesis Ocular Adnexal Lymphoma law hemic and lymphatic diseases RNA Ribosomal 16S medicine Humans Chlamydiaceae Polymerase chain reaction Chlamydia psittaci Chlamydia biology Eye Neoplasms Hematology Lymphoma B-Cell Marginal Zone Psittacosis biology.organism_classification medicine.disease Lymphoma Chlamydophila psittaci Chlamydiales Immunology Florida |
| Zdroj: | British journal of haematology. 142(2) |
| ISSN: | 1365-2141 |
| Popis: | Ocular Adnexal Lymphomas (OALs) are the most common tumors of the eye, the majority being extranodal mucosa-associated lymphoid tissue (MALT) lymphomas. Association with Chlamydia psittaci was described in some geographic areas. OAL response to antibiotic therapy was reported in cases not harboring Chlamydia psittaci DNA, suggesting that other bacterial infection might be implicated in the pathogenesis. We examined 49 MALT OALs for bacterial DNA using two distinct polymerase chain reaction techniques based on universal bacterial primers. No bacterial DNA that could be implicated in OAL pathogenesis was detected, suggesting that bacterial infection is not associated with OAL in South Florida. |
| Databáze: | OpenAIRE |
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