Combined conjunctival rotational autograft with 0.02% mitomycin C in primary pterygium surgery: a long-term follow-up study
| Autor: | Lulu L Cheng, Mary Ho, Alvin L. Young, Vishal Jhanji, Nicole Tsim |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Alkylating Agents medicine.medical_specialty Time Factors genetic structures Pterygium excision Long term follow up Mitomycin Pterygium surgery Visual Acuity Ophthalmologic Surgical Procedures Pterygium Intraoperative Period Cellular and Molecular Neuroscience Recurrence hemic and lymphatic diseases Cornea medicine Humans Autografts Aged Aged 80 and over business.industry digestive oral and skin physiology Mitomycin C Outcome measures Middle Aged medicine.disease eye diseases Sensory Systems Surgery Ophthalmology medicine.anatomical_structure Female sense organs Ophthalmic Solutions Historical control business Conjunctiva Follow-Up Studies |
| Zdroj: | British Journal of Ophthalmology. 99:1396-1400 |
| ISSN: | 1468-2079 0007-1161 |
| Popis: | To compare the long-term outcomes of primary pterygium surgery with combined conjunctival rotational autograft and mitomycin C (CRA-MMC), mitomycin C alone (MMC) and limbal conjunctival autograft (LCAU).The outcomes of primary pterygium excision followed by conjunctival rotational autograft (CRA) combined with intraoperative 0.02% MMC for 5 min (group 1, CRA-MMC, n=61) were compared with historical control groups consisting of, pterygium excision with MMC (group 2, n=47), and, pterygium excision with limbal conjunctival autograft (LCAU) (group 3, n=29). The main outcome measures were recurrence rate and complications.The mean follow-up period was 101±3 months, 138±2 and 137±2 months in the CRA-MMC, MMC and LCAU groups respectively. Recurrence was noted in one patient (1.6%) in the CRA-MMC, 12 patients with MMC (25.5%) and 2 patients with LCAU (6.9%). The difference in recurrence rate between CRA-MMC and MMC was statistically significant (p0.001). Early postoperative complications included 3 conjunctival cysts (1 from the CRA-MMC, 2 with MMC alone), 2 symblephara (1 in the MMC group, 1 in the LCAU group), and 1 granuloma in the CRA-MMC group.Pterygium excision followed by CRA-MMC or LCAU are effective means of preventing recurrence. The use of CRA-MMC in pterygium excision may be considered for cases where conventional autograft harvesting is contraindicated or when large grafts for double-head pterygium are required. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|