Impact of Secretory Immunoglobulin A Level on Dental Caries Experience in Asthmatic Children
| Autor: | Salwa Aldahlawi, Adel Hussien, Abla Arafa |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Saliva Orthodontics Secretory Immunoglobulin A Significant negative correlation Gastroenterology 03 medical and health sciences fluids and secretions 0302 clinical medicine stomatognathic system Disease severity Internal medicine Healthy control medicine Children Asthma 030219 obstetrics & reproductive medicine business.industry Secretory immunoglobulin A 030206 dentistry medicine.disease Asthmatic children stomatognathic diseases Pediatrics Perinatology and Child Health Dental caries Periodontics Oral Surgery business Caries experience Research Article |
| Zdroj: | International Journal of Clinical Pediatric Dentistry |
| ISSN: | 0975-1904 0974-7052 |
| DOI: | 10.5005/jp-journals-10005-1663 |
| Popis: | Objectives To assess the association between different factors in saliva and dental caries experience in children with bronchial asthma. Materials and methods A total of 60 asthmatic children and 60 healthy controls of both genders with age ranging from 4- to 12-year-old. The asthmatics were grouped according to disease severity into mild, moderate, or severe asthma. All the children were clinically examined to assess their dental caries experience (deft/DMFT), and stimulated saliva samples were collected to measure the saliva pH, flow rate, ά-amylase, and secretory immunoglobulin A (sIgA)-level changes. The data were statistically analyzed using the SPSS program (v. 23) to test for significance at p ≤ 0.05. Results Asthmatic children presented significantly higher deft mean value (6.77 ± 1.69), as well as significantly reduced stimulated saliva flow (0.82 ± 0.2) and sIgA (29.42 ± 6.31) when compared to healthy control. The sIgA of asthmatics showed statistically significant negative correlation with deft and DMFT. Severe asthmatics presented significantly the lowest sIgA mean level (23.61 ± 5.33) and the most reduced saliva flow rate (0.64 ± 0.20). Conclusion The reduction in saliva flow rate and secretory immunoglobulin A render asthmatic children more prone to increased dental caries progression mainly of primary dentition. How to cite this article Arafa A, AlDahlawi S, Hussien A, et al. Impact of Secretory Immunoglobulin A Level on Dental Caries Experience in Asthmatic Children. Int J Clin Pediatr Dent 2019;12(5):414–418. |
| Databáze: | OpenAIRE |
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