The diagnostic performance of cardiac magnetic resonance in detection of myocardial involvement in AL amyloidosis
| Autor: | Romana Rysava, Michal Fikrle, Ivan Spicka, Petr Kuchynka, Jan Straub, Tomáš Paleček, Martin Masek, Aleš Linhart |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Physiology Population Cardiomyopathy Magnetic Resonance Imaging Cine 030204 cardiovascular system & hematology Sensitivity and Specificity 03 medical and health sciences Ventricular Dysfunction Left 0302 clinical medicine Physiology (medical) Internal medicine AL amyloidosis medicine Late gadolinium enhancement Humans cardiovascular diseases 030212 general & internal medicine education Aged education.field_of_study Ejection fraction business.industry Reproducibility of Results General Medicine Amyloidosis medicine.disease Amyloid heart disease Echocardiography cardiovascular system Cardiology Female Amyloid cardiomyopathy Cardiac magnetic resonance business Cardiomyopathies |
| Zdroj: | Clinical physiology and functional imaging. 36(3) |
| ISSN: | 1475-097X |
| Popis: | Summary Background The non-invasive assessment of amyloid heart disease may be challenging. Cardiac magnetic resonance (CMR) represents a method of choice for assessment of left ventricular (LV) morphology and function, and it also provides a unique possibility to evaluate the presence of amyloid deposition by the late gadolinium enhancement (LGE) technique. However, so far, published studies have not been consistent in terms of described LGE patterns associated with amyloid cardiomyopathy. Aims To compare echocardiographic and CMR assessment of LV morphology and function and to evaluate the presence and pattern of LGE in a population of patients with AL amyloid cardiomyopathy. Methods Twenty-two consecutive patients with newly diagnosed AL amyloid cardiomyopathy and without contraindications to CMR were comprehensively examined by echocardiography and CMR. Results Echocardiography and CMR did not differ in the evaluation of interventricular septal thickness, LV end-diastolic diameter and ejection fraction. Significant differences were found between echocardiographic and CMR estimates of LV end-diastolic volume (P |
| Databáze: | OpenAIRE |
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