Combination therapy of scalp electro-acupuncture and medication for the treatment of Parkinson's disease: A systematic review and meta-analysis
| Autor: | Hong-Mei Sun, Jing Feng, Yi Zhang, Zhen-Yu Guo, Yuan Chai, Ling Ma, Cong Gai, Tian-Yao Qiang, Wan-Di Feng, Hao-Jie Ma |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0303 health sciences
medicine.medical_specialty Parkinson's disease Combination therapy business.industry medicine.disease lcsh:RZ409.7-999 030226 pharmacology & pharmacy Confidence interval law.invention Clinical trial 03 medical and health sciences 0302 clinical medicine Complementary and alternative medicine Randomized controlled trial Rating scale law Meta-analysis Relative risk Physical therapy Medicine business lcsh:Miscellaneous systems and treatments 030304 developmental biology |
| Zdroj: | Journal of Traditional Chinese Medical Sciences, Vol 6, Iss 1, Pp 26-34 (2019) |
| ISSN: | 2095-7548 |
| Popis: | Objective: To summarize the current clinical evidence related to the therapeutic effects and safety of adjuvant scalp electro-acupuncture (SEA) treatment for Parkinson's disease in China. Methods: Following the PRISMA statement, seven electronic databases were searched to retrieve randomized controlled clinical trials that used SEA combined with medication as the treatment intervention, and medication as the control. RevMan 5.3 was used to analyze outcomes, including the Unified Parkinson's Disease Rating Scale (UPDRS), Webster scale, effectiveness rate, and UPDRS III. Results: Nine randomized controlled trials, with certain methodological flaws and risks of bias, were included that involved 474 participants. SEA combined with medication was more effective than medication alone in overall therapeutic effects, as evidenced by total UPDRS scores (mean difference (MD): 7.15, 95% confidence interval [CI] 0.24 to 14.07, P = .04), Webster scores (MD: 1.60, 95% CI 0.20 to 2.99, P = .03), and effectiveness rate (risk ratio: 1.35, 95% CI 1.19 to 1.54, P |
| Databáze: | OpenAIRE |
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