| Autor: |
Meng Guo, Kai Yang, Nancy D. Kock, Roger Daley, William Dzwierzynski, John LoGiudice, Patrick Hettinger, Cameron Best, Anne Argenta |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Hand (New York, N.Y.). |
| ISSN: |
1558-9455 |
| Popis: |
Background: Dupuytren disease creates thickened cords of the palmar fascia, leading to progressive flexion contractures that severely hinder hand function. Collagenase clostridium histolyticum (CCH) injection is a common, minimally invasive alternative to surgical excision of these cords. The impact of CCH injection on the histological architecture of Dupuytren cords has not been studied extensively. Methods: A series of 10 CCH-injected cords were evaluated histologically. Cellularity, architecture, and connective tissue organization were compared against uninjected Dupuytren cords and normal palmar fascia. Results: No significant histopathological differences between CCH-injected and CCH-uninjected cords were identified. Conclusions: Dupuytren cords do not demonstrate histological changes with prior exposure to CCH. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
