Well-Developed Coronary Collateral Circulation Is Associated With Higher Thrombus Burden in the Setting of ST-Segment Elevation Myocardial Infarction
| Autor: | Aslı Vural, Devrim Kurt, Ahmet Karagöz, Zeki Yüksel Günaydın |
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| Rok vydání: | 2022 |
| Předmět: |
Coronary Thrombosis
Myocardial Infarction Collateral Circulation Coronary Angiography Electrocardiography Percutaneous Coronary Intervention Risk Factors Coronary Circulation Albumins Humans ST Elevation Myocardial Infarction Clinical Investigation Cardiology and Cardiovascular Medicine Coronary Collaterals in STEMI: Do Small Roads Lead to Clot? |
| Zdroj: | Tex Heart Inst J |
| ISSN: | 1526-6702 0730-2347 |
| DOI: | 10.14503/thij-21-7574 |
| Popis: | Background This study investigated the relationship between coronary collateral circulation (CCC) and intracoronary thrombus burden in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction (STEMI). CCC and thrombus burden are predictive of clinical outcomes in patients with STEMI. Methods Patients with STEMI undergoing primary percutaneous coronary intervention were enrolled (n = 172). CCC was graded according to the Cohen–Rentrop classification. Patients were classified as insufficient (grade 0 or 1, n = 134) or well-developed (grade 2 or 3; n = 38) CCC. The Thrombolysis in Myocardial Infarction scale was used to evaluate intra-coronary thrombus burden. The low-thrombus-burden group comprised those with grades 0 to 2, and the high-thrombus-burden group comprised those with grades 3 or 4. Results Right coronary artery infarcts had a 13.830-fold higher chance of having well-developed CCC than did left anterior descending artery infarcts (P < .001). Circumflex artery infarcts had a 7.904-fold higher chance of well-developed CCC than did left anterior descending artery infarcts (P = .016). High thrombus burden was associated with a 4.393-fold higher chance for well-developed CCC than was low thrombus burden (P = .030). Low albumin levels were related to a greater chance of having well-developed CCC (P = .046). Conclusion Patients with well-developed CCC have higher thrombus burden than do those with insufficient CCC. Because well-developed CCC is an indicator of more severe underlying lesions, we speculate that patients with severe lesions are more prone to experience more complicated STEMI with high thrombus burden. |
| Databáze: | OpenAIRE |
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