Thyroglobulin and Thyroglobulin Autoantibodies Measurement Using the Automated KRYPTOR® Platform in Patients with Differentiated Thyroid Carcinoma
| Autor: | Frederik A. Verburg, L. Giovanella, Caputo M, Toffalori E, Luca Ceriani |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism medicine.medical_treatment Concordance Clinical Biochemistry Thyroglobulin Biochemistry Gastroenterology Thyroid carcinoma Automation Young Adult Endocrinology Internal medicine Humans Medicine In patient Thyroid Neoplasms Aged Autoantibodies Immunoassay business.industry Weak relationship Biochemistry (medical) Autoantibody Cell Differentiation General Medicine Middle Aged Fully automated Linear Models Female business Large group |
| Zdroj: | Hormone and Metabolic Research. 43:728-730 |
| ISSN: | 1439-4286 0018-5043 |
| DOI: | 10.1055/s-0031-1285868 |
| Popis: | The aim of the present study is 1) to compare our established manual thyroglobulin (Tg) and Tg autoantibody (TgAb) immunoassays to the automated KRYPTOR® platform from the same manufacturer, in a large group of DTC patients and 2) to evaluate whether a change in assay methods could be made without disrupting the serial monitoring pattern. Sera from 160 patients with histologically proven DTC were obtained and Tg and TgAb measured by manual immunoassays and a fully automated platform. We found an excellent agreement between the 2 methods for Tg measurement (R=0.9888, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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