Visual acuity correlates with multimodal imaging-based categories of central serous chorioretinopathy
| Autor: | Supriya Arora, Dmitrii S. Maltsev, Ramesh Venkatesh, Claudio Iovino, Enrico Peiretti, Jay Chhablani, Nikitha Gurram Reddy, Alexei N. Kulikov, Deepika Parameshwarappa, Tarun Arora, Filippo Tatti, Ram Snehith Pulipaka, Niroj Kumar Sahoo, Sumit Randhir Singh |
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| Přispěvatelé: | Arora, Supriya, Maltsev, Dmitrii S, Sahoo, Niroj Kumar, Parameshwarappa, Deepika C, Iovino, Claudio, Arora, Tarun, Kulikov, Alexei N, Tatti, Filippo, Venkatesh, Ramesh, Reddy, Nikitha Gurram, Pulipaka, Ram Snehith, Singh, Sumit Randhir, Peiretti, Enrico, Chhablani, Jay |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Visual acuity genetic structures Visual Acuity Logistic regression Multimodal Imaging Article Foveal Ophthalmology Medicine Humans Fluorescein Angiography Retrospective Studies Multimodal imaging business.industry Correction Baseline data Odds ratio eye diseases Confidence interval Serous fluid Cross-Sectional Studies Central Serous Chorioretinopathy Female sense organs medicine.symptom business Tomography Optical Coherence |
| Zdroj: | Eye (Lond) |
| Popis: | Objective To evaluate visual acuity (VA) and factors influencing VA using new multimodal imaging-based classification of central serous chorioretinopathy (CSCR). Methods Retrospective, observational and cross-sectional study on 229 naive eyes diagnosed as CSCR with available baseline data and multimodal imaging. Each case was classified into (i) simple/complex/atypical; (ii) primary/recurrent/resolved; (iii) persistent or not; (iv) outer retinal atrophy(ORA) present/absent; (v) foveal involvement present/absent; and (vi) macular neovascularization(MNV) present/absent. Best corrected visual acuity (BCVA) was correlated to the classification as well as every parameter of the classification. Results Median BCVA was 0.18 logMAR [95% Confidence Interval (CI)0.16-0.18] with median duration of complaints of one month (95% CI,6.14-13.0 months). Age of the patient (r = -0.24, p = 0.002) and duration of the disease (r = -0.32, p < 0.001) correlated significantly with BCVA. Logistic regression model showed that older age [odds ratio (OR) = 0.96, p = 0.05], female gender (OR = 2.45, p = 0.046), presence of ORA(OR = 0.34, p = 0.012),and foveal involvement(OR = 0.18, p = 0.007) were statistically significantly associated with poorer BCVA. Eyes classified as complex, persistent CSCR, with ORA or foveal involvement demonstrated lower BCVA compared to those with simple, non-persistent CSCR, without ORA or without foveal involvement (p < 0.05). Eyes with complex CSCR (p < 0.001), atypical CSCR(p = 0.025), persistent subretinal fluid (SRF) (p = 0.001) and those with ORA (p < 0.001) demonstrated a trend towards severe visual loss. Prevalence of persistent SRF, recurrent episodes and ORA was significantly higher among eyes with complex CSCR (p < 0.001) while there was no difference in prevalence of resolved cases (p = 0.07), foveal involvement (p = 0.28) and MNV (p = 0.45) between simple and complex cases. Conclusion There is a strong correlation between VA and foveal involvement and ORA using the new classification. Thus, the objective parameters of the classification can be incorporated in establishing the treatment guidelines for CSCR. |
| Databáze: | OpenAIRE |
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