Reactivity of posterior cortical electroencephalographic alpha rhythms during eyes opening in cognitively intact older adults and patients with dementia due to Alzheimer's and Lewy body diseases
| Autor: | Claudio Babiloni, Ivan Lorenzo, Roberta Lizio, Susanna Lopez, Federico Tucci, Raffaele Ferri, Andrea Soricelli, Flavio Nobili, Dario Arnaldi, Francesco Famà, Carla Buttinelli, Franco Giubilei, Virginia Cipollini, Marco Onofrj, Fabrizio Stocchi, Laura Vacca, Peter Fuhr, Ute Gschwandtner, Gerhard Ransmayr, Dag Aarsland, Lucilla Parnetti, Moira Marizzoni, Fabrizia D'Antonio, Carlo De Lena, Bahar Güntekin, Ebru Yıldırım, Lutfu Hanoğlu, Görsev Yener, Duygu Hünerli Gündüz, John Paul Taylor, Julia Schumacher, Ian McKeith, Giovanni B. Frisoni, Maria Francesca De Pandis, Laura Bonanni, Claudio Del Percio, Giuseppe Noce |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Lewy Body Disease
lzheimer's disease (AD) Aging Rest Dementia with Lewy Bodies (DLB) dementia with Lewy Bodies (DLB) desynchronization of alpha rhythms exact low-resolution brain electromagnetic source tomography (eLORETA) eyes closed eyes open resting state electroencephalographic (EEG) rhythms Alzheimer Disease mental disorders Humans Cognitive Dysfunction Aged Cerebral Cortex Eyes open General Neuroscience Resting State Electroencephalographic (EEG) Rhythms Electroencephalography Exact Low-Resolution Brain Electromagnetic Source Tomography (eLORETA) Alpha Rhythm Eyes closed Alzheimer's disease (AD) Desynchronization of Alpha Rhythms Lewy Bodies Neurology (clinical) Geriatrics and Gerontology Developmental Biology |
| Popis: | Please modify the Abstract as follows:Here we tested if the reactivity of posterior resting-state electroencephalographic (rsEEG) alpha rhythms from the eye-closed to the eyes-open condition may differ in patients with dementia due to Lewy Bodies (DLB) and Alzheimer's disease (ADD) as a functional probe of the dominant neural synchronization mechanisms regulating the vigilance in posterior visual systems.We used clinical, demographical, and rsEEG datasets in 28 older adults (Healthy), 42 DLB, and 48 ADD participants. The eLORETA freeware was used to estimate cortical rsEEG sources.Results showed a substantial (> -10%) reduction in the posterior alpha activities during the eyes-open condition in 24 Healthy, 26 ADD, and 22 DLB subjects. There were lower reductions in the posterior alpha activities in the ADD and DLB groups than in the Healthy group. That reduction in the occipital region was lower in the DLB than in the ADD group.These results suggest that DLB patients may suffer from a greater alteration in the neural synchronization mechanisms regulating vigilance in occipital cortical systems compared to ADD patients. H2020 Marie S. Curie ITN-ETN project Italian Ministry of Health to the IRCCS SDN of Naples, IRCCS OASI of Troina, and IRCCS San Raffaele Pisana of Rome |
| Databáze: | OpenAIRE |
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