Need for expertise in mitral valve regurgitation
| Autor: | Thierry Letourneau, Elena Galli, Erwan Donal |
|---|---|
| Přispěvatelé: | Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre hospitalier universitaire de Nantes (CHU Nantes), Jonchère, Laurent, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system Mitral valve Internal medicine medicine Mitral valve prolapse cardiovascular diseases 030212 general & internal medicine Systole ComputingMilieux_MISCELLANEOUS ventricular arrhythmia Annulus (mycology) Mitral regurgitation business.industry medicine.disease Anatomic Variation [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system Editorial medicine.anatomical_structure [SDV.IB.IMA] Life Sciences [q-bio]/Bioengineering/Imaging Ventricle annular disjunction cardiovascular system Cardiology mitral regurgitation Cardiology and Cardiovascular Medicine Mitral valve regurgitation business |
| Zdroj: | Open heart Open heart, 2019, 6 (1), pp.e001039. ⟨10.1136/openhrt-2019-001039⟩ Open heart, British Cardiovascular Society, 2019, 6 (1), pp.e001039. ⟨10.1136/openhrt-2019-001039⟩ Open Heart |
| ISSN: | 2053-3624 |
| DOI: | 10.1136/openhrt-2019-001039⟩ |
| Popis: | The mitral annulus is a three-dimensional, saddle-shaped structure exhibiting dynamic conformational changes during the cardiac cycle.1 The normal annulus contracts and increases in saddle-shaped non-planarity during systole.2 3 Such annular dynamics are important for the balanced distribution of the mechanical stresses imposed by the left ventricle (LV) on the mitral valve apparatus.4 5 Mitral annular disjunction (MAD) is an anatomic abnormality of the mitral annulus described as a wide separation between the atrium–mitral valve junction and the LV attachment that is appreciable on both gross and histological examination. During reparative surgery for mitral valve prolapse (MVP), surgical evaluation can detect MAD as a superior displacement or atrialisation of the posterior leaflet base. Although MAD is found in a large proportion of patients with myxomatous MVP,6 it has also been described as an anatomic variation of mitral annulus morphology. MAD leads to paradoxical annular enlargement and flattening during systole, increasing leaflets and chordae stress, which may accelerate the degenerative process of mitral valve apparatus. It has been suggested that the … |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|