Incidence, risk factors, and feto-maternal outcomes of inappropriate birth weight for gestational age among singleton live births in Qatar: A population-based study

Autor: Ghassan Abdoh, Mai AlQubaisi, Gheyath K. Nasrallah, Nader Al-Dewik, Sawsan Al-Obaidly, Rana Al-Jurf, Salma Younes, Tawa Olukade, Husam Salama, Noor Salama, Hilal Al Rifai, Palli Valapila Abdulrouf, Tom Farrell, Muthanna Samara, Sara Hammuda
Rok vydání: 2021
Předmět:
Male
Epidemiology
Physiology
Maternal Health
Abnormal fetal growth
Fetal Macrosomia
pregnancy and at postpartum
Families
Endocrinology
Medical Conditions
nursing
Pregnancy
Risk Factors
inappropriate fetal growth
Medicine and Health Sciences
Birth Weight
Medicine
Children
Multidisciplinary
Singleton
Incidence
Incidence (epidemiology)
Pregnancy Outcome
Obstetrics and Gynecology
Gestational age
Physiological Parameters
Infant
Small for Gestational Age
Premature Birth
Female
Infants
Research Article
Endocrine Disorders
Science
Birth weight
Diabetes Mellitus
Humans
Gestational Diabetes
Qatar
Retrospective Studies
Data collection
business.industry
Body Weight
Infant
Newborn
Biology and Life Sciences
Neonates
Infant
Overweight
Infant
Low Birth Weight
Population based study
Age Groups
Medical Risk Factors
Metabolic Disorders
People and Places
Birth
Women's Health
Population Groupings
business
Developmental Biology
Demography
Zdroj: PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258967 (2021)
PLoS ONE
ISSN: 1932-6203
Popis: Background Abnormal fetal growth can be associated with factors during pregnancy and at postpartum. Objective In this study, we aimed to assess the incidence, risk factors, and feto-maternal outcomes associated with small-for-gestational age (SGA) and large-for-gestational age (LGA) infants. Methods We performed a population-based retrospective study on 14,641 singleton live births registered in the PEARL-Peristat Study between April 2017 and March 2018 in Qatar. We estimated the incidence and examined the risk factors and outcomes using univariate and multivariate analysis. Results SGA and LGA incidence rates were 6.0% and 15.6%, respectively. In-hospital mortality among SGA and LGA infants was 2.5% and 0.3%, respectively, while for NICU admission or death in labor room and operation theatre was 28.9% and 14.9% respectively. Preterm babies were more likely to be born SGA (aRR, 2.31; 95% CI, 1.45–3.57) but male infants (aRR, 0.57; 95% CI, 0.4–0.81), those born to parous (aRR 0.66; 95% CI, 0.45–0.93), or overweight (aRR, 0.64; 95% CI, 0.42–0.97) mothers were less likely to be born SGA. On the other hand, males (aRR, 1.82; 95% CI, 1.49–2.19), infants born to parous mothers (aRR 2.16; 95% CI, 1.63–2.82), or to mothers with gestational diabetes mellitus (aRR 1.36; 95% CI, 1.11–1.66), or pre-gestational diabetes mellitus (aRR 2.58; 95% CI, 1.8–3.47) were significantly more likely to be LGA. SGA infants were at high risk of in-hospital mortality (aRR, 226.56; 95% CI, 3.47–318.22), neonatal intensive care unit admission or death in labor room or operation theatre (aRR, 2.14 (1.36–3.22). Conclusion Monitoring should be coordinated to alleviate the risks of inappropriate fetal growth and the associated adverse consequences.
Databáze: OpenAIRE
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