Incidence, risk factors, and feto-maternal outcomes of inappropriate birth weight for gestational age among singleton live births in Qatar: A population-based study
Autor: | Ghassan Abdoh, Mai AlQubaisi, Gheyath K. Nasrallah, Nader Al-Dewik, Sawsan Al-Obaidly, Rana Al-Jurf, Salma Younes, Tawa Olukade, Husam Salama, Noor Salama, Hilal Al Rifai, Palli Valapila Abdulrouf, Tom Farrell, Muthanna Samara, Sara Hammuda |
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Rok vydání: | 2021 |
Předmět: |
Male
Epidemiology Physiology Maternal Health Abnormal fetal growth Fetal Macrosomia pregnancy and at postpartum Families Endocrinology Medical Conditions nursing Pregnancy Risk Factors inappropriate fetal growth Medicine and Health Sciences Birth Weight Medicine Children Multidisciplinary Singleton Incidence Incidence (epidemiology) Pregnancy Outcome Obstetrics and Gynecology Gestational age Physiological Parameters Infant Small for Gestational Age Premature Birth Female Infants Research Article Endocrine Disorders Science Birth weight Diabetes Mellitus Humans Gestational Diabetes Qatar Retrospective Studies Data collection business.industry Body Weight Infant Newborn Biology and Life Sciences Neonates Infant Overweight Infant Low Birth Weight Population based study Age Groups Medical Risk Factors Metabolic Disorders People and Places Birth Women's Health Population Groupings business Developmental Biology Demography |
Zdroj: | PLoS ONE, Vol 16, Iss 10 (2021) PLoS ONE, Vol 16, Iss 10, p e0258967 (2021) PLoS ONE |
ISSN: | 1932-6203 |
Popis: | Background Abnormal fetal growth can be associated with factors during pregnancy and at postpartum. Objective In this study, we aimed to assess the incidence, risk factors, and feto-maternal outcomes associated with small-for-gestational age (SGA) and large-for-gestational age (LGA) infants. Methods We performed a population-based retrospective study on 14,641 singleton live births registered in the PEARL-Peristat Study between April 2017 and March 2018 in Qatar. We estimated the incidence and examined the risk factors and outcomes using univariate and multivariate analysis. Results SGA and LGA incidence rates were 6.0% and 15.6%, respectively. In-hospital mortality among SGA and LGA infants was 2.5% and 0.3%, respectively, while for NICU admission or death in labor room and operation theatre was 28.9% and 14.9% respectively. Preterm babies were more likely to be born SGA (aRR, 2.31; 95% CI, 1.45–3.57) but male infants (aRR, 0.57; 95% CI, 0.4–0.81), those born to parous (aRR 0.66; 95% CI, 0.45–0.93), or overweight (aRR, 0.64; 95% CI, 0.42–0.97) mothers were less likely to be born SGA. On the other hand, males (aRR, 1.82; 95% CI, 1.49–2.19), infants born to parous mothers (aRR 2.16; 95% CI, 1.63–2.82), or to mothers with gestational diabetes mellitus (aRR 1.36; 95% CI, 1.11–1.66), or pre-gestational diabetes mellitus (aRR 2.58; 95% CI, 1.8–3.47) were significantly more likely to be LGA. SGA infants were at high risk of in-hospital mortality (aRR, 226.56; 95% CI, 3.47–318.22), neonatal intensive care unit admission or death in labor room or operation theatre (aRR, 2.14 (1.36–3.22). Conclusion Monitoring should be coordinated to alleviate the risks of inappropriate fetal growth and the associated adverse consequences. |
Databáze: | OpenAIRE |
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