1H NMR spectroscopy and MVA to evaluate the effects of caulerpin-based diet on diplodus sargus lipid profiles

Autor: Antonio Terlizzi, Frederico Almada, Serena Felline, Laura Del Coco, Biagio D'Aniello, Francesco Paolo Fanizzi, Ernesto Mollo, Federica Angilè, Laura Magliozzi, Chiara Roberta Girelli
Přispěvatelé: Coco, Laura Del, Felline, Serena, Girelli, Chiara Roberta, Angile', Federica, Magliozzi, Laura, Almada, Frederico, D'Aniello, Biagio, Mollo, Ernesto, Terlizzi, Antonio, Fanizzi, Francesco P., Angilè, Federica
Jazyk: angličtina
Rok vydání: 2018
Předmět:
0301 basic medicine
Food Chain
Metabolite
Proton Magnetic Resonance Spectroscopy
Diplodus sargus
Pharmaceutical Science
biological invasion
Metabolomic
Secondary metabolite
03 medical and health sciences
chemistry.chemical_compound
Metabolomics
Nutraceutical
NMR spectroscopy
Chlorophyta
Drug Discovery
Fatty Acids
Omega-3
Mediterranean Sea
Caulerpa
14. Life underwater
Food science
Pharmacology
Toxicology and Pharmaceutics (miscellaneous)
lcsh:QH301-705.5
Multivariate Analysi
Introduced Specie
chemistry.chemical_classification
biology
secondary metabolites
Animal
Flesh
Drug Discovery3003 Pharmaceutical Science
Lipid metabolism
Diplodus
Caulerpa cylindracea
biology.organism_classification
Lipid Metabolism
metabolomics
Sea Bream
030104 developmental biology
chemistry
lcsh:Biology (General)
Indole
Green algae
Diplodus sargu
Biological invasion
Polyunsaturated fatty acid
Zdroj: Marine drugs 16 (2018). doi:10.3390/md16100390
info:cnr-pdr/source/autori:Del Coco L.; Felline S.; Girelli C.R.; Angile F.; Magliozzi L.; Almada F.; D'Aniello B.; Mollo E.; Terlizzi A.; Fanizzi F.P./titolo:1H NMR spectroscopy and MVA to evaluate the effects of caulerpin-based diet on diplodus sargus lipid profiles/doi:10.3390%2Fmd16100390/rivista:Marine drugs/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:16
Marine Drugs, Vol 16, Iss 10, p 390 (2018)
Marine Drugs
Volume 16
Issue 10
DOI: 10.3390/md16100390
Popis: The biological invasion of the green algae Caulerpa cylindracea represents a serious scientific and public issue in the Mediterranean Sea, essentially due to strong modifications both to habitat structure and native benthic communities. Although alterations in health status and changes in flesh quality of some marine species (dietary exposed to C. cylindracea) have been observed, no studies on cause-effect relationships have been carried out. Here, for the first time, through a controlled feeding experiment followed by 1H NMR Spectroscopy and multivariate analysis (PCA, OPLS-DA), we showed that caulerpin taken with diet is directly responsible of changes observed in metabolic profile of fish flesh, including alteration of lipid metabolism, in particular with a reduction of &omega
3 PUFA content. The potential of caulerpin to directly modulate lipid metabolism opens up new questions about causal mechanism triggered by algal metabolite also in view of a possible exploitation in the nutraceutical/medical field.
Databáze: OpenAIRE
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