Combined use of chemical and biological compounds to control hookworm
| Autor: | Vinícius Longo Ribeiro Vilela, José Antônio Correia Lima, Samilla Alves Sobral, Fernando Luiz Tobias, Hugo Leonardo André Genier, Freitas Soares, Carolina Magri Ferraz, D B L Junior, M R D A Lima, Fabio Ribeiro Braga, J.V. de Araújo |
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| Rok vydání: | 2020 |
| Předmět: |
Ancylostomatoidea
030231 tropical medicine Combined use Biology Nematophagous fungus Vaseline Albendazole 030207 dermatology & venereal diseases 03 medical and health sciences Hookworm Infections 0302 clinical medicine Ivermectin Dogs Ascomycota medicine Animals Anthelmintic Dog Diseases Feces Anthelmintics Biological Products Traditional medicine Drug Synergism General Medicine biology.organism_classification Larva Animal Science and Zoology Parasitology Ancylostoma caninum medicine.drug |
| Zdroj: | Journal of helminthology. 94 |
| ISSN: | 1475-2697 |
| Popis: | The aim of this study was to evaluate the combined use of different chemical (albendazole, ivermectin, glycerine and Vaseline) and biological (Monacrosporium thaumasium) compounds in the control of Ancylostoma caninum. Infective larvae of A. caninum were obtained from coprocultures of positive faeces from naturally infected dogs. We used 1% ivermectin, 1% albendazole, 100% glycerine, 100% Vaseline and an isolate of the nematophagous fungus M. thaumasium (NF34), alone or in combinations. Next, an experimental test was set up with 16 groups in microtubes, with a 24-h interaction. The groups (G1 to G15) that contained any chemical or biological compound (NF34) and/or their combined use (chemical + biological) showed a difference in relation to the control group, except G5 – Vaseline 100% without combinations. It was concluded that, even on an experimental basis, the combined use of anthelmintic drugs with biological control was efficient; however, more studies must be carried out in order to elucidate the synergistic action between chemical and biological compounds to be used in the effective control of hookworms in the future. |
| Databáze: | OpenAIRE |
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