Chemopreventive effect of coffee against colorectal cancer and hepatocellular carcinoma

Autor: Johanna C. Arroyave, Fabián Cortés-Mancera, Sarah Röthlisberger, Manuel Moreno-Ceballos
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: International Journal of Food Properties, Vol 22, Iss 1, Pp 536-555 (2019)
ISSN: 1532-2386
1094-2912
Popis: Cancer is a complex and evolving disease that is the leading cause of death in the twenty-first century, and colorectal and liver cancers specifically are in the top 10 cancer types in terms of incidence and mortality; therefore, there has been a shift towards researching prevention strategies, amongst which chemoprevention is key. Coffee is a natural product that has recently gained importance in this area due to its chemopreventive potential and its high level of consumption worldwide. In this review, recent epidemiological and experimental evidence of the chemopreventive effect of coffee against these two types of cancer are presented, and the role of the different compounds present in coffee in cell proliferation, apoptosis and response to oxidative stress are discussed.
Databáze: OpenAIRE
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